Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Wiertz, E.J.H.J. +80 more
core +1 more source
Determinou-se a evolução da imunidade colostral contra o herpesvírus bovino tipo 1 (BHV-1) através de análise de amostras de soro de terneiras coletadas às 6, 12 e 24 horas após o nascimento, semanalmente dos 7 dias até os 63 dias de idade, e mensalmente
Sílvia de Oliveira Hübner +3 more
doaj +1 more source
Identification and localization of the structural proteins of anguillid herpesvirus 1 [PDF]
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Leroy, B +45 more
core +1 more source
pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread.
The herpes simplex virus (HSV)-1 protein pUL21 is essential for efficient virus replication and dissemination. While pUL21 has been shown to promote multiple steps of virus assembly and spread, the molecular basis of its function remained unclear.
Tomasz H Benedyk +17 more
doaj +1 more source
A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB. [PDF]
Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 ...
Stewart, James P. +20 more
core +1 more source
Evolutionary History of Endogenous Human Herpesvirus 6 Reflects Human Migration out of Africa. [PDF]
Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result, ∼70 million people harbor the genome of one of these viruses in every cell of their body. Until now, it has been largely unknown if 1) these integrations are ancient, 2)
Zimmermann, Cosima +18 more
core +2 more sources
Phylogenetic relationships in the family Alloherpesviridae [PDF]
Phylogenetic relationships among herpesviruses (HVs) of mammals, birds, and reptiles have been studied extensively, whereas those among other HVs are relatively unexplored.
Kelley, G.O. +5 more
core +1 more source
Encephalitis associated with human herpesvirus-7 infection in an immunocompetent adult
Background Primary Human herpesvirus-7 (HHV-7) infection usually occurs during childhood and causes several clinical manifestations: mainly exanthem subitum (roseola infantum), followed by a lifelong latent state with possible reactivation in case of ...
Mónica Parra +7 more
doaj +1 more source
Phylogenetic and molecular epidemiological studies reveal evidence of multiple past recombination events between infectious laryngotracheitis viruses. [PDF]
In contrast to the RNA viruses, the genome of large DNA viruses such as herpesviruses have been considered to be relatively stable. Intra-specific recombination has been proposed as an important, but underestimated, driving force in herpesvirus evolution.
Sang-Won Lee +7 more
doaj +1 more source
Recombination in human herpesvirus-8 strains from Uganda and evolution of the K15 gene
Human herpesvirus-8 (HHV-8) is believed to be the aetiological agent of Kaposi’s sarcoma (KS). KS accounts for half the reported cancer cases in Uganda, and occurs in endemic and epidemic [human immunodeficiency virus (HIV)-associated] forms. We confirmed a high prevalence (74%) of HHV-8 antibodies in 114 HIV-negative Ugandan blood donors, and ...
Kakoola, D +6 more
openaire +3 more sources

