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Viral Evolution and Adaptation

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Viral evolution: Accordion adaptations go viral.

Nature reviews. Microbiology, 2012
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Modelling the evolution of viral oncogenesis [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2019
Most human oncogenic viruses share several characteristics, such as being DNA viruses, having long (co)evolutionary histories with their hosts and causing either latent or chronic infections. They can reach high prevalences while causing relatively low case mortality, which makes them quite fit according to virulence evolution theory.
Murall, Carmen Lia, Alizon, Samuel
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Defensin-driven viral evolution. [PDF]

PLoS Pathogens, 2020
Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralization of
Karina Diaz, Ciara T Hu, Youngmee Sul, Beth A Bromme, Nicolle D Myers, Ksenia V Skorohodova, Anshu P Gounder, Jason G Smith   +7 more
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Viral evolution during primary infection in immunocompromised hosts. [PDF]

PLoS Computational Biology
The immune response to viral infection is a delicate balance. By perturbing this balance, immunodeficiencies are expected to influence within-host viral evolution.
Morgan Craig, Xiaoyan Deng, David V McLeod   +2 more
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Evolution goes viral [PDF]

Nature Ecology and Evolution, 2021
exaly   +3 more sources

The evolution of viral diversity

, 2012
This thesis focuses on the population dynamics of three antigenically diverse RNA viruses: dengue, influenza and HIV-1. It comprises a set of studies highlighting the roles of structural constraints on critical antigenic determinants, interactions between immune responses to different antigenic types, host lifespan, and the degree of mixing between ...
Wikramaratna, Paul Silva
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The biophysical landscape of viral evolution. [PDF]

Proc Natl Acad Sci U S A
Wilke CO.
europepmc   +3 more sources

Viral Quasispecies Evolution [PDF]

Microbiology and Molecular Biology Reviews, 2012
SUMMARYEvolution of RNA viruses occurs through disequilibria of collections of closely related mutant spectra or mutant clouds termed viral quasispecies. Here we review the origin of the quasispecies concept and some biological implications of quasispecies dynamics.
Domingo, Esteban, Sheldon, Julie, Perales, Celia   +2 more
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Editorial: Decoding the genetics of viral evolution. [PDF]

Front Genet, 2022
Ali H, Rahman SA, Akhtar J, Haque SA, Ali S.   +4 more
europepmc   +4 more sources