Results 1 to 10 of about 220,643 (261)
Defensin-driven viral evolution. [PDF]
PLoS Pathogens, 2020 Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralization of
Karina Diaz +7 more
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Viral evolution during primary infection in immunocompromised hosts. [PDF]
PLoS Computational BiologyThe immune response to viral infection is a delicate balance. By perturbing this balance, immunodeficiencies are expected to influence within-host viral evolution.
Morgan Craig +2 more
doaj +2 more sources
The biophysical landscape of viral evolution. [PDF]
Proc Natl Acad Sci U S AWilke CO.
europepmc +3 more sources
Viral Quasispecies Evolution [PDF]
Microbiology and Molecular Biology Reviews, 2012 SUMMARYEvolution of RNA viruses occurs through disequilibria of collections of closely related mutant spectra or mutant clouds termed viral quasispecies. Here we review the origin of the quasispecies concept and some biological implications of quasispecies dynamics.
Domingo, Esteban +2 more
openaire +3 more sources
Editorial: Decoding the genetics of viral evolution. [PDF]
Front Genet, 2022 Ali H +4 more
europepmc +4 more sources
Topology of viral evolution [PDF]
Proceedings of the National Academy of Sciences, 2013 Significance Evolution is mediated not only by random mutations over a number of generations (vertical evolution), but also through the mixture of genomic material between individuals of different lineages (horizontal evolution). The standard evolutionary representation, the phylogenetic tree, faithfully represents the former but not ...
Chan, Joseph Minhow +2 more
openaire +3 more sources
Computationally designed proteins mimic antibody immune evasion in viral evolution [PDF]
ImmunityJeremy Luban +2 more
exaly +2 more sources
Viral evolution and epidemiology [PDF]
Current Opinion in Infectious Diseases, 1997 This review highlights recent research on viral evolution and its use towards understanding disease pathogenesis and epidemiology. The development of techniques such as enzymatic amplification of viral genomes and automated sequencing has led to a dramatic increase in the amount of sequence information from clinical samples. These sequences (RNA or DNA,
Katrin, Leitmeyer, Rebeca, Rico-Hesse
openaire +2 more sources
Scientific Reports, 2023 Shared needles are a possible iatrogenic and hematogenous inanimate vector of African Swine Fever virus (ASFV) in farm conditions. To evaluate that possible transmission, sixty, 4-week-old pigs were procured from an ASF free herd free. Upon arrival, pigs
Muhammad Salman +6 more
doaj +1 more source