Results 21 to 30 of about 238,327 (306)
EMBO Molecular Medicine, 2013 The gastrointestinal tract is a principal route of entry and site of persistence of human immunodeficiency virus type 1 (HIV‐1). The intestinal mucosa, being rich of cells that are the main target of the virus, represents a primary site of viral ...
Mariangela Cavarelli +3 more
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Viral diseases and human evolution [PDF]
Memórias do Instituto Oswaldo Cruz, 2000 The interaction of man with viral agents was possibly a key factor shaping human evolution, culture and civilization from its outset. Evidence of the effect of disease, since the early stages of human speciation, through pre-historical times to the present suggest that the types of viruses associated with man changed in time.
Élcio de Souza Leal +1 more
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mBio, 2015 Influenza virus infections are a global public health problem, with a significant impact of morbidity and mortality from both annual epidemics and pandemics.
Louis M. Schwartzman +5 more
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Theoretical Population Biology, 2002 Viruses vastly outnumber their host cells and must present a huge selective pressure. It is also becoming evident that only a small percent of the eukaryotic genome codes for molecules involved in cellular structures and functions, and that much of the remainder may have a viral origin.
Bamford, D, Burnett, R, Stuart, D
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Alvira : comparative genomics of viral strains [PDF]
, 2007 The Alvira tool is a general purpose multiple sequence alignment viewer with a special emphasis on the comparative analysis of viral genomes. This new tool has been devised specifically to address the problem of the simultaneous analysis of a large ...
Fremez, Romain +7 more
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mBio, 2011 Secondary bacterial infections increase disease severity of influenza virus infections and contribute greatly to increased morbidity and mortality during pandemics.
John C. Kash +10 more
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iScience, 2022 Summary: The difficulty to unambiguously identify the various subsets of mononuclear phagocytes (MNPs) of the intestinal lamina propria has hindered our understanding of the initial events occurring after mucosal exposure to HIV-1.Here, we compared the ...
Mariangela Cavarelli +10 more
doaj +1 more source
The evolution of viral emergence [PDF]
Proceedings of the National Academy of Sciences, 2006 The current uncertainty over whether H5N1 avian influenza virus will successfully adapt to human transmission highlights the importance of understanding the evolutionary basis of viral emergence, particularly the respective roles played by ecology and genetics in allowing viruses to establish productive transmission networks in new host species.
openaire +2 more sources
Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection [PDF]
, 2002 Although antiviral agents which block human immunodeficiency virus (HIV) replication can result in long-term suppression of viral loads to undetectable levels in plasma, long-term therapy fails to eradicate virus, which generally rebounds after a single ...
Ruiz, L +9 more
core +1 more source
mBio, 2018 Influenza virus hemagglutinin (HA) surface glycoprotein is currently the primary target of licensed influenza vaccines. Recently, broadly reactive antibodies that target the stalk region of the HA have become a major focus of current novel vaccine ...
Jae-Keun Park +9 more
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