Epstein–Barr virus reactivation influences clonal evolution in human herpesvirus‐8‐related lymphoproliferative disorders [PDF]
BackgroundHuman herpesvirus‐8 (HHV8) is a lymphotropic virus associated with different lymphoproliferative disorders, including primary effusion lymphoma (PEL), multicentric Castleman’s disease (MCD), diffuse large B‐cell lymphomas, not otherwise specified, and the rare entity known as germinotropic lymphoproliferative disorder (GLPD). In PELs and GLPD
Massimo Granai +13 more
openaire +3 more sources
Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits [PDF]
The tripartite terminase complex of herpesviruses assembles in the cytoplasm of infected cells and exploits the host nuclear import machinery to gain access to the nucleus, where capsid assembly and genome-packaging occur. Here we analyzed the structure and conservation of nuclear localization signal (NLS) sequences previously identified in herpes ...
Rajeshwer S, Sankhala +2 more
openaire +2 more sources
Human cytomegalovirus intrahost evolution—a new avenue for understanding and controlling herpesvirus infections [PDF]
Abstract Human cytomegalovirus (HCMV) is exquisitely adapted to the human host, and much research has focused on its evolution over long timescales spanning millennia. Here, we review recent data exploring the evolution of the virus on much shorter timescales, on the order of days or months.
Renzette, Nicholas +3 more
openaire +4 more sources
Divergent Antiviral Mechanisms of Two Viperin Homeologs in a Recurrent Polyploid Fish
Polyploidy and subsequent diploidization provide genomic opportunities for evolutionary innovations and adaptation. The researches on duplicated gene evolutionary fates in recurrent polyploids have seriously lagged behind that in paleopolyploids with ...
Cheng-Yan Mou +24 more
doaj +1 more source
The core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin encoded by bovine herpesvirus 4 was acquired from an ancestor of the African buffalo [PDF]
peer reviewedThe Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To investigate the origin and evolution of the
Markine-Goriaynoff, N +17 more
core +1 more source
Herpesviruses that Infect Fish
Herpesviruses are host specific pathogens that are widespread among vertebrates. Genome sequence data demonstrate that most herpesviruses of fish and amphibians are grouped together (family Alloherpesviridae) and are distantly related to herpesviruses of
Moshe Kotler, Larry Hanson, Arnon Dishon
doaj +1 more source
Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]
The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA +5 more
core +1 more source
HISTORY AND CURRENT STATUS OF MAREK'S DISEASE IN TURKEYS
Mareks disease (MD), caused by a highly contagious and oncogenic herpesvirus, causes immunosuppression and tumours in chickens. Although several reports on occurring lymphomas (MD-like conditions) in turkeys were published in the past less attention has
Awad Shehata +2 more
doaj +1 more source
Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B. +2 more
core +1 more source
Fusion of piggyBac-like transposons and herpesviruses occurs frequently in teleosts
Background Endogenous viral elements play important roles in eukaryotic evolution by giving rise to genetic novelties. Herpesviruses are a large family of DNA viruses, most of which do not have the ability to endogenize into host genomes.
Yusuke Inoue +6 more
doaj +1 more source

