Results 101 to 110 of about 4,275,336 (320)

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

INFLUENCE OF HERPES SIMPLEX VIRUS PERSISTENCE UPON PRODUCTION OF CYTOKINES BY IMMUNOCOMPETENT CELLS IN RHEUMATOID ARTHRITIS

Медицинская иммунология, 2014
. Using modern immunological methods of studies, we investigated some immunopathogenetic aspects of rheumatoid arthritis complicated by chronic herpesvirus infection.
N. A. Pronina, V. S. Sviridova, E. N. Kologrivova, L. V. Еliseeva, I. O. Naslednikova, O. I. Urazova, V. V. Novitsky, O. V. Voronkova, N. A. Sukhalentseva, E. B. Gorbunova   +9 more
doaj   +1 more source

Features of effector lymphocyte subsets in patients with uveal melanoma in recurrent and chronic herpesvirus infection

Инфекция и иммунитет, 2022
The aim of the study is to conduct a comparative analysis of percentages for peripheral blood effector lymphocyte subsets in patients with uveal melanoma manifested by recurrent and chronic herpesvirus infection.
N. V. Balatskaya, S. V. Saakyan, E. B. Myakoshina, I. G. Kulikova, G. I. Krichevskaya   +4 more
doaj   +1 more source

Toll-like receptor sensing of human herpesvirus infection

Front. Cell. Inf. Microbio., 2012
Toll-like receptors (TLRs) are evolutionarily conserved pathogen sensors that constitute the first line of defense in the human immune system. Herpesviruses are prevalent throughout the world and cause significant disease in the human population. Sensing
J. West, Sean M. Gregory, B. Damania
semanticscholar   +1 more source

Co‐reactivation of the human herpesvirus alpha subfamily (herpes simplex virus‐1 and varicella zoster virus) in a critically ill patient with COVID‐19

British Journal of Dermatology, 2020
Coronavirus disease 2019 (COVID-19) is already well known globally1 . The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 infection) causes a spectrum of severe clinical manifestations, which leads to a high rate of intensive care unit (ICU ...
R. Xu, Ying Zhou, L. Cai, Lin Wang, J. Han, X. Yang, Jiyan Chen, C. Ma, L. Shen   +8 more
semanticscholar   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

Human herpesvirus 6.

Clinical Infectious Diseases, 2020
The development of techniques for the culture of lymphoid cells and the isolation of viruses that infect these cells led to the discovery of human herpesvirus (HHV) 6 in 1986.
L. Strausbaugh, M. Caserta, David J. Mock, S. Dewhurst   +3 more
semanticscholar   +1 more source

A Mechanistic Model of rAAV Production in Synthetic Cell Lines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan, Han‐Jung Kuo, Yu‐Chieh Lin, Yen‐An Lu, Wei‐Shou Hu, Qi Zhang   +5 more
wiley   +1 more source

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]

, 2015
Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TRIVEDI, PANKAJ   +6 more
core   +4 more sources

Can epilepsy be predicted after the first febrile seizure? Insights from machine learning of postictal EEG

Epileptic Disorders, EarlyView.
Abstract Objective Febrile seizures (FS) are the most common seizures in childhood, yet identifying children at risk of developing epilepsy after the first FS remains challenging. We aimed to evaluate the prognostic potential of machine learning (ML) algorithms applied to post‐febrile seizure electroencephalography (EEG) recordings.
Boran Şekeroğlu, Hüseyin Öztoprak, Özlem Yayıcı Köken, Hatice Demir, Mehpare Sarı Yanartaş, Deniz Yılmaz, Burçin Şanlıdağ, Ayşegül Neşe Çıtak Kurt   +7 more
wiley   +1 more source