Advanced therapy medicinal products (ATMPs) – An analysis of the global regulatory status
British Journal of Clinical Pharmacology, EarlyView.Abstract Background A rapid progress in the development of advanced therapy medicinal products (ATMPs) has taken place over the past decades. The ATMPs hold great potential but face challenges in the clinical development and the regulatory process.
Allan Cramer +4 more
wiley +1 more source
Turning vaccine allergy CDSS into a global trust pipeline: Equity, auditability, and workflow safety. [PDF]
J Allergy Clin Immunol GlobSrikanth M, Vijayasimha M.
europepmc +1 more source
Co‐design–related approaches in medication safety for people with dementia: A scoping review
British Journal of Clinical Pharmacology, EarlyView.Background People with dementia manage complex medication regimens and face a heightened risk of medication‐related harm. Co‐design approaches are increasingly being used to develop interventions/tools to improve medication safety in this population. Objectives To describe how co‐design has been applied in developing interventions or tools related to ...
Zena El‐kadomi +3 more
wiley +1 more source
European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism
BJS (British Journal of Surgery), EarlyView., 2020 Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz +3 more
wiley +1 more source
Vaccine confidence and hesitancy among mothers of children under six years of age in Salvador, Brazil: The role of sociodemographic factors and health service experience. [PDF]
PLoS OnePalombo CNT +8 more
europepmc +1 more source
British National Formulary Guidance on prescribing in pregnancy: A descriptive cross‐sectional study
British Journal of Clinical Pharmacology, EarlyView.Aim To assess how well pregnancy‐specific guidance within the British National Formulary supports healthcare professionals to facilitate safe and effective medication use. Methods We performed a manifest content analysis of the text of all pregnancy sections within British National Formulary drug monographs, with inductive and iterative coding.
Hannah Johnson +9 more
wiley +1 more source
Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
British Journal of Clinical Pharmacology, EarlyView.Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
COVID-19 vaccination hesitancy in pediatrics: a systematic review. [PDF]
Syst RevAmanat N +3 more
europepmc +1 more source
‘Let's talk about the weather’: The activist curriculum and global climate change education
British Educational Research Journal, EarlyView.Abstract Activist movements have garnered significant global attention on a range of sustainability issues, often involving collectives of citizens coming together. Invoked is the idea of citizens informed to act, emerging not from a common‐sense understanding of everyday life, but rather from a deep political understanding of the world—one that is ...
Richard Pountney
wiley +1 more source