Results 211 to 220 of about 75,754 (257)
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Chromosoma, 1999
The properties of heterochromatin are reconsidered in the context of our present understanding of gene silencing, telomeric and centromeric properties, position-effect variegation and X-chromosome inactivation. It is proposed that the chromatin in heterochromatic chromosomal regions is generally similar in its molecular composition to that in silenced ...
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The properties of heterochromatin are reconsidered in the context of our present understanding of gene silencing, telomeric and centromeric properties, position-effect variegation and X-chromosome inactivation. It is proposed that the chromatin in heterochromatic chromosomal regions is generally similar in its molecular composition to that in silenced ...
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Heterochromatin definition and function
Nature Reviews Molecular Cell Biology, 2023Heterochromatin is a key characteristic of eukaryotic genomes. Since its cytological description nearly 100 years ago, our understanding of heterochromatin features and functions, including transcription repression and genome stability, have continuously evolved.
Oliver Bell +4 more
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Deconfining heterochromatin for expression
Nature Cell Biology, 2021Lineage-specific gene expression programs in multicellular organisms are controlled by balanced ON and OFF signals, amongst which heterochromatin regulates expression by restricting activation cues. A study now provides insights into mammalian heterochromatin organisation, function and interplay with lineage-specific transcription factors.
Adam Burton, Maria-Elena Torres-Padilla
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Unfolding the mysteries of heterochromatin
Current Opinion in Genetics and Development, 1998The function of heterochromatin has not been well understood. Recent studies, however, demonstrate that heterochromatin is essential for proper chromosome behavior. The silencing of euchromatic genes by heterochromatin has been exploited to understand the molecular nature of heterochromatin.
Lori L Wallrath
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Chromosoma, 1985
Comparative fluorescence studies on the chromosome of ten species of acridid grasshoppers, with varying amounts and locations of C-band positive heterochromatin, indicate that the only regions to fluoresce differentially are those that C-band. Within a given species there is a marked tendency for groups of chromosomes to accumulate heterochromatin with
B, John +3 more
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Comparative fluorescence studies on the chromosome of ten species of acridid grasshoppers, with varying amounts and locations of C-band positive heterochromatin, indicate that the only regions to fluoresce differentially are those that C-band. Within a given species there is a marked tendency for groups of chromosomes to accumulate heterochromatin with
B, John +3 more
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NOR associations with heterochromatin
Cytogenetics and Cell Genetics, 2008Associations between nucleolus organizer regions (NORs) and non-acrocentric chromosomes were scored in 2,800 metaphase spreads from PHA-stimulated lymphocyte cultures (48 h) from 14 individuals. The preparations were both silver stained and C-banded.
C M, Tuck-Muller +3 more
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Heterochromatin and chromosome aberrations
Chromosoma, 1969The chromosome breaking effect of mitomycin C, methyl methanesulfonate, maleic hydrazide, 8-ethoxycaffeine and gamma rays on the primary root meristematic cells of Nigella damascena was studied. All the agents tested except 8-ethoxycaffeine, produced relatively fewer aberrations, when compared to Vicia faba cells, though both the species have nearly ...
A T, Natarajan, G, Ahnström
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Heterochromatin, colchicine, and karyotype
Chromosoma, 1965Species of Chilocorus differ in chromosome number owing to centric fusion of metacentric chromosomes. The concomitant loss of arms is tolerated because in all unfused chromosomes one arm is completely heterochromatic, the other euchromatic. Under the influence of colchicine, the arms of unfused and fused chromosomes contract differentially.
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The Origin of Heterochromatin in Eukaryotes
Russian Journal of Genetics, 2002This study is an attempt to reconstruct the stages of the evolution of heterochromatin in eukaryotes. According to the hypothesis put forward in the work, the origin of satellite DNAs (stDNAs) was directly related to certain functional characteristics of DNA polymerases, and stDNAs themselves are products of accidental slippage at replication ...
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