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Nanopore-based sequencing of active DNA replication reveals key principles of metazoan replication dynamics. [PDF]
Sci AdvHan D +3 more
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Known and predicted genes in the heterochromatin of Drosophila melanogaster.
, 2003 DIMITRI, Patrizio +3 more
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Correction to 'Heterochromatome wide analyses reveal MBD2 as a phase separation scaffold for heterochromatin compartmentalization and composition'. [PDF]
Nucleic Acids Reseuropepmc +1 more source
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Unfolding the mysteries of heterochromatin
Current Opinion in Genetics and Development, 1998The function of heterochromatin has not been well understood. Recent studies, however, demonstrate that heterochromatin is essential for proper chromosome behavior. The silencing of euchromatic genes by heterochromatin has been exploited to understand the molecular nature of heterochromatin.
Lori L Wallrath
exaly +3 more sources
Chromosoma, 1995
The Second International Workshop on Drosophila Heterochromatin, held in Honolulu from January 4-7, 1995, brought together about 70 scientists from the US, Canada, Germany, Italy, Russia, and the Netherlands. After the first of these international meetings, five years ago, Mary Lou Pardue and Wolfgang Hennig, in these columns, commented on its ...
E, Zuckerkandl, W, Hennig
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The Second International Workshop on Drosophila Heterochromatin, held in Honolulu from January 4-7, 1995, brought together about 70 scientists from the US, Canada, Germany, Italy, Russia, and the Netherlands. After the first of these international meetings, five years ago, Mary Lou Pardue and Wolfgang Hennig, in these columns, commented on its ...
E, Zuckerkandl, W, Hennig
openaire +2 more sources
Chromosoma, 1999
The properties of heterochromatin are reconsidered in the context of our present understanding of gene silencing, telomeric and centromeric properties, position-effect variegation and X-chromosome inactivation. It is proposed that the chromatin in heterochromatic chromosomal regions is generally similar in its molecular composition to that in silenced ...
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The properties of heterochromatin are reconsidered in the context of our present understanding of gene silencing, telomeric and centromeric properties, position-effect variegation and X-chromosome inactivation. It is proposed that the chromatin in heterochromatic chromosomal regions is generally similar in its molecular composition to that in silenced ...
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Heterochromatin definition and function
Nature Reviews Molecular Cell Biology, 2023Heterochromatin is a key characteristic of eukaryotic genomes. Since its cytological description nearly 100 years ago, our understanding of heterochromatin features and functions, including transcription repression and genome stability, have continuously evolved.
Oliver Bell +4 more
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Deconfining heterochromatin for expression
Nature Cell Biology, 2021Lineage-specific gene expression programs in multicellular organisms are controlled by balanced ON and OFF signals, amongst which heterochromatin regulates expression by restricting activation cues. A study now provides insights into mammalian heterochromatin organisation, function and interplay with lineage-specific transcription factors.
Adam Burton, Maria-Elena Torres-Padilla
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