Results 251 to 260 of about 133,661 (356)

Heterochromatin variation in chromosomes of Anopheles (Nyssorhynchus) darlingi Root and A.(N.) nuneztovari Gabaldón (Diptera: Culicidae) [PDF]

, 2000
Míriam Silva Rafael, Wanderli Pedro Tadei   +1 more
openalex   +1 more source

RepeatOBserver: Tandem Repeat Visualisation and Putative Centromere Detection

Molecular Ecology Resources, Volume 25, Issue 7, October 2025.
ABSTRACT Tandem repeats play an important role in centromere structure, subtelomeric regions, DNA methylation, recombination and the regulation of gene activity. Analysis of their distribution in genomes offers a potential means for predicting putative centromere locations, which continues to be a challenge for genome annotation.
Cassandra Elphinstone, Rob Elphinstone, Marco Todesco, Loren H. Rieseberg   +3 more
wiley   +1 more source

Insight into the mechanisms and dysregulation of KMT5C-H4K20me3 in cancer. [PDF]

Epigenetics
Son J, Kasinski AL.
europepmc   +1 more source

cTAGE5/MEA6 Regulates LBR Localization to Maintain Nuclear Envelope Integrity and Safeguard Against Aging

Aging Cell, Volume 24, Issue 10, October 2025.
cTAGE5 regulates LBR trafficking between the ER and the nucleus membrane to maintain the integrity of both the ER and the nuclear envelope. cTAGE5 KO results in LBR retention in the ER, reduced stability, and subsequent disruption of nuclear envelope integrity. ABSTRACT cTAGE5/MEA6 plays a pivotal role in COPII complex assembly, ER‐to‐Golgi trafficking,
Yaqing Wang, Pengyu Sun, Fuqiang Yang, Tiantian Ma, Junwan Fan, Lei Shi, Nan Li, Fei Gao, Kangmin He, Zhiheng Xu   +9 more
wiley   +1 more source

Histone H4 Acetylation of Euchromatin and Heterochromatin Is Cell Cycle Dependent and Correlated with Replication Rather Than with Transcription [PDF]

, 2000
Zuzana Jasencakova, Armin Meister, Joachim Walter, Bryan M. Turner, Ingo Schubert   +4 more
openalex   +1 more source

KDM4 Orchestrates Epigenomic Remodeling of Senescent Cells and Potentiates the Senescence‐Associated Secretory Phenotype

Aging Cell, Volume 24, Issue 10, October 2025.
The chromatin accessibility landscape of senescent cells is remodeled, with a set of activated transcription factors physically binding to the enhancers and promoters of senescence‐associated genes, including those encoding SASP factors. Events such as epigenomic reprogramming and KDM4‐mediated histone demethylation (H3K9/H3K36) enable SASP expression ...
Boyi Zhang, Qilai Long, Shanshan Wu, Qixia Xu, Shuling Song, Liu Han, Min Qian, Xiaohui Ren, Hanxin Liu, Jing Jiang, Jianming Guo, Xiaoling Zhang, Xing Chang, Qiang Fu, Eric W.‐F. Lam, Judith Campisi, James L. Kirkland, Yu Sun   +17 more
wiley   +1 more source

Intrinsically disordered region of Clr4/Suv39 regulates its enzymatic activity and ensures heterochromatin spreading. [PDF]

Nucleic Acids Res
Nakamura R, Hayashi A, Nakagawa R, Yoshimura Y, Horikoshi N, Kurumizaka H, Nakayama JI.   +6 more
europepmc   +1 more source

Conservation of Heterochromatin Protein 1 Function [PDF]

, 2000
Guozheng Wang, Alicia Ma, Cheok-man Chow, David A. Horsley, Nicholas R. Brown, Ian G. Cowell, Prim B. Singh   +6 more
openalex   +1 more source

Enhanced C/EBPα Function Extends Healthspan and Lifespan in the African Turquoise Killifish

Aging Cell, Volume 24, Issue 10, October 2025.
Mutation of the upstream open reading frame (uORF) in the CEBPA gene in short‐lived killifish, resulting in unrestrained activity of the C/EBPα transcription factor, is associated with increased healthspan and lifespan. ABSTRACT The transcription factor CCAAT/enhancer binding protein alpha (C/EBPα) regulates cell differentiation, proliferation, and ...
Christine Müller, Joscha S. Muck, Kirill Ustyantsev, Gertrud Kortman, Josephine Hartung, Eugene Berezikov, Cornelis F. Calkhoven   +6 more
wiley   +1 more source

Unravelling heterochromatin [PDF]

Nature Reviews Molecular Cell Biology, 2005
openaire   +1 more source