Results 251 to 260 of about 124,493 (360)

Interpreting the Origins and Functions of Noncoding RNAs From the Ribosomal Genes

Journal of Cellular Physiology, Volume 240, Issue 8, August 2025.
The Ribosomal RNA genes are repressed by the p14/p19ARF tumour suppressor. Activity of an upstream promoter duplication is normally blocked by Transcription Termination Factor 1 (TTF1). However, ARF displaces TTF1, inducing gene repression by “Noncoding‐RNA‐Induced Promoter Occlusion” or RIPO. TTF1 may control other Noncoding RNA generated under stress.
Tom Moss, Dany S. Sibai, Frédéric Lessard   +2 more
wiley   +1 more source

DDM1 Maintains Heterochromatin by Regulating Histone Variants. [PDF]

Int J Mol Sci
Sun Y, Xie Q, Chu H, Lv B, Xie L, Zhang Q.   +5 more
europepmc   +1 more source

Rapid Identification of DUX4::IGH Fusion in Acute Lymphoblastic Leukemia

eJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Introduction DUX4 is rearranged and overexpressed in a subgroup of acute lymphoblastic leukemia (ALL) with B‐precursor phenotype, with a favorable outcome. Even though characteristic gene expression signature as well as surface expression of CD2/CD371 could be a hallmark of DUX4‐rearranged ALL, actual detection of DUX4 rearrangement is ...
Kyoko Moritani, Minenori Eguchi‐Ishimae, Mari Tezuka‐Kagajo, Machiko Miyamoto, Mayumi Iwamoto, Sanae Kawakami, Ryota Nakamura, Kozo Nagai, Sawa Tomomatsu, Tsuyoshi Imai, Yasushi Ishida, Hisamichi Tauchi, Eiichi Ishii, Mariko Eguchi   +13 more
wiley   +1 more source

Analysis of histone modification interplay reveals two distinct domains in facultative heterochromatin in Pyricularia oryzae. [PDF]

Commun Biol
Dang TA, Morimoto A, Kobayashi N, Pham K, Ikeda KI, Nakayashiki H.   +5 more
europepmc   +1 more source

Histone H4 Acetylation of Euchromatin and Heterochromatin Is Cell Cycle Dependent and Correlated with Replication Rather Than with Transcription [PDF]

, 2000
Zuzana Jasencakova, Armin Meister, Joachim Walter, Bryan M. Turner, Ingo Schubert   +4 more
openalex   +1 more source

Analyzing the Challenges and Opportunities Associated With Harnessing New Antibiotics From the Fungal Microbiome

MicrobiologyOpen, Volume 14, Issue 4, August 2025.
Graphical abstract illustrating the multifaceted approach to harnessing fungal microbiome diversity for antibiotic discovery. Key elements include historical insights, modern genomic tools, and innovative biotechnological strategies for isolating and enhancing fungal antibiotic production.
Md. Sakhawat Hossain, Md. Al Amin, Sirajul Islam, Hasan Imam, Liton Chandra Das, Shahin Mahmud   +5 more
wiley   +1 more source

The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate. [PDF]

Nat Cell Biol
Marin HC, Allen C, Simental E, Martin EW, Panning B, Al-Sady B, Buchwalter A.   +6 more
europepmc   +1 more source

Conservation of Heterochromatin Protein 1 Function [PDF]

, 2000
Guozheng Wang, Alicia Ma, Cheok-man Chow, David A. Horsley, Nicholas R. Brown, Ian G. Cowell, Prim B. Singh   +6 more
openalex   +1 more source

Osteoarthritis: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 8, August 2025.
A schematic illustration of the pathogenesis and emerging therapeutic strategies for OA, including: risk factors and molecular mechanisms of OA, joint changes between healthy and OA conditions, and current emerging therapeutic approaches for OA. Abbreviations: IA: intra‐articular injection; EVs: extracellular vesicles. ABSTRACT Osteoarthritis (OA) is a
Wei Liu, Ning‐Yi Guo, Jian‐Quan Wang, Bing‐Bing Xu   +3 more
wiley   +1 more source

Positive coactivator PC4 shows dynamic nucleolar distribution required for rDNA transcription and protein synthesis. [PDF]

Cell Commun Signal
Kaypee S, Ochiai K, Shima H, Matsumoto M, Alam M, Ikura T, Kundu TK, Igarashi K.   +7 more
europepmc   +1 more source