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Polycomb Repressive Complexes 1 and 2 are recruited independently to pericentromeric heterochromatin in response to hypomethylation in mouse embryonic stem cells

Dimova-Vasileva S, Stepanova O, Hay D, Pickup KE, Gautier P, Murphy LC, Kumar Y, Adams IR, Pennings S, Meehan RR.   +9 more
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Heterochromatin

Chromosoma, 1999
The properties of heterochromatin are reconsidered in the context of our present understanding of gene silencing, telomeric and centromeric properties, position-effect variegation and X-chromosome inactivation. It is proposed that the chromatin in heterochromatic chromosomal regions is generally similar in its molecular composition to that in silenced ...
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Deconfining heterochromatin for expression

Nature Cell Biology, 2021
Lineage-specific gene expression programs in multicellular organisms are controlled by balanced ON and OFF signals, amongst which heterochromatin regulates expression by restricting activation cues. A study now provides insights into mammalian heterochromatin organisation, function and interplay with lineage-specific transcription factors.
Adam Burton, Maria-Elena Torres-Padilla
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Reinterpreting pericentromeric heterochromatin

Current Opinion in Plant Biology, 2006
In fission yeast, pericentromeric heterochromatin is directly responsible for the sister chromatid cohesion that assures accurate chromosome segregation. In plants, however, heterochromatin and chromosome segregation appear to be largely unrelated: chromosome transmission is impaired by mutations in cohesion but not by mutations that affect ...
Christopher N, Topp, R Kelly, Dawe
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Heterochromatin and chromosome aberrations

Chromosoma, 1969
The chromosome breaking effect of mitomycin C, methyl methanesulfonate, maleic hydrazide, 8-ethoxycaffeine and gamma rays on the primary root meristematic cells of Nigella damascena was studied. All the agents tested except 8-ethoxycaffeine, produced relatively fewer aberrations, when compared to Vicia faba cells, though both the species have nearly ...
A T, Natarajan, G, Ahnström
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‘Heterochromatin’

Nature, 1950
J R, BAKER, H G, CALLAN
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Heterochromatin

2013
M. Zaratiegui, R.A. Martienssen
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Heterochromatin

2023
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Heterochromatin

2008
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