Results 21 to 30 of about 612,093 (259)

Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects. [PDF]

Mem Inst Oswaldo Cruz
da Trindade NS, Valentini MB, Rognon A, Mendes TMF, Gomes MS, Allegretti SM, Grunau C, Cabral FJ.   +7 more
europepmc   +2 more sources

Heterochromatin protein 1 alpha (HP1α) undergoes a monomer to dimer transition that opens and compacts live cell genome architecture. [PDF]

Nucleic Acids Res
Lou J, Deng Q, Zhang X, Bell CC, Das AB, Bediaga NG, Zlatic CO, Johanson TM, Allan RS, Griffin MDW, Paradkar P, Harvey KF, Dawson MA, Hinde E.   +13 more
europepmc   +2 more sources

Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1. [PDF]

J Biol Chem, 2017
Liu Y, Qin S, Lei M, Tempel W, Zhang Y, Loppnau P, Li Y, Min J.   +7 more
europepmc   +2 more sources

Heterochromatin protein 1 (HP1) is intrinsically required for post-transcriptional regulation of Drosophila Germline Stem Cell (GSC) maintenance. [PDF]

Sci Rep, 2019
Casale AM, Cappucci U, Fanti L, Piacentini L.   +3 more
europepmc   +3 more sources

Characterization of Hepatoma-Derived Growth Factor-Related Protein 2 Interactions with Heterochromatin

Cells, 2023
The expression of genetic information is tightly controlled by chromatin regulatory proteins, including those in the heterochromatin gene repression family.
Sarah C. Wistner, Ian A. MacDonald, Karly A. Stanley, Nathaniel A. Hathaway   +3 more
doaj   +1 more source

Domains of Heterochromatin Protein 1 Required forDrosophila melanogasterHeterochromatin Spreading [PDF]

Genetics, 2009
AbstractCentric regions of eukaryotic genomes are packaged into heterochromatin, which possesses the ability to spread along the chromosome and silence gene expression. The process of spreading has been challenging to study at the molecular level due to repetitious sequences within centric regions. A heterochromatin protein 1 (HP1) tethering system was
Diane E. Cryderman, Tulle Hazelrigg, Michael W. Vitalini, Hongbo Yang, Lori L. Wallrath, Karrie A. Hines, Kaitlin M. Flannery, Craig A. Mizzen   +7 more
openaire   +3 more sources

C. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity

eLife, 2021
Caenorhabditis elegans expresses human Werner syndrome protein (WRN) orthologs as two distinct proteins: MUT-7, with a 3′−5′ exonuclease domain, and CeWRN-1, with helicase domains. How these domains cooperate remains unclear.
Tsung-Yuan Hsu, Bo Zhang, Noelle D L'Etoile, Bi-Tzen Juang   +3 more
doaj   +1 more source

How HP1 Post-Translational Modifications Regulate Heterochromatin Formation and Maintenance

Cells, 2020
Heterochromatin Protein 1 (HP1) is a highly conserved protein that has been used as a classic marker for heterochromatin. HP1 binds to di- and tri-methylated histone H3K9 and regulates heterochromatin formation, functions and structure.
Raquel Sales-Gil, Paola Vagnarelli
doaj   +1 more source

From Effective Interactions Extracted Using Hi-C Data to Chromosome Structures in Conventional and Inverted Nuclei [PDF]

PRX Life 1, 013010 (2023), 2023
Contact probabilities between loci, separated by arbitrary genomic distance, for a number of cell types have been reported using genome-wide chromosome conformation capture (Hi-C) experiments. How to extract the effective interaction energies between active euchromatin (A) and inactive heterochromatin (B) directly from the experimental data, without an
arxiv   +1 more source

Revisiting the role of heterochromatin protein 1 in DNA repair [PDF]

Journal of Cell Biology, 2009
Heterochromatin protein 1 (HP1) is a conserved factor critical for heterochromatin organization and gene silencing. It is recruited to chromatin by its direct interaction with H3K9me (methylated lysine 9 residue of histone H3), an epigenetic mark for silenced chromatin. Now, Luijsterburg et al. (Luijsterburg, M.S., C. Dinant, H. Lans, J.
Ball, Alexander R, Yokomori, Kyoko
openaire   +5 more sources