Results 41 to 50 of about 1,693,917 (277)

ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing. [PDF]

, 2009
Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications, including DNA methylation, histone H3 dimethylation at Lys9 (H3K9me2) and monomethylation at Lys27 (H3K27me1).
Bernatavichute, Yana V, Cokus, Shawn, Feng, Suhua, Jacob, Yannick, Jacobsen, Steven E, Johnson, Lianna M, LeBlanc, Chantal A, Michaels, Scott D, Pellegrini, Matteo, Stroud, Hume   +9 more
core   +1 more source

The Human Protein PRR14 Tethers Heterochromatin to the Nuclear Lamina during Interphase and Mitotic Exit

Cell Reports, 2013
The nuclear lamina is a protein meshwork that lies under the inner nuclear membrane of metazoan cells. One function of the nuclear lamina is to organize heterochromatin at the inner nuclear periphery.
Andrey Poleshko, Katelyn M. Mansfield, Caroline C. Burlingame, Mark D. Andrake, Neil R. Shah, Richard A. Katz   +5 more
doaj   +1 more source

Epigenetic silencing in Friedreich ataxia is associated with depletion of CTCF (CCCTC-binding factor) and antisense transcription. [PDF]

PLoS ONE, 2009
BACKGROUND:Over 15 inherited diseases are caused by expansion of triplet-repeats. Friedreich ataxia (FRDA) patients are homozygous for an expanded GAA triplet-repeat sequence in intron 1 of the FXN gene.
Irene De Biase, Yogesh K Chutake, Paul M Rindler, Sanjay I Bidichandani   +3 more
doaj   +1 more source

Candida albicans repetitive elements display epigenetic diversity and plasticity [PDF]

, 2016
Transcriptionally silent heterochromatin is associated with repetitive DNA. It is poorly understood whether and how heterochromatin differs between different organisms and whether its structure can be remodelled in response to environmental signals. Here,
A Ellahi, A Pidoux, A Selmecki, aF Straight, BD Strahl, C Ketel, C Li, C Trapnell, Ca Froyd, CJ Merrick, D Kadosh, DE Gottschling, GD Shankaranarayana, H Chibana, H Chibana, J Haran, J Huang, J Huang, J Nakayama, J Pérez-Martín, J Wendland, JC Tanny, JS Smith, Ka Morano, KR Hansen, L Vasiljeva, LH Freitas-Junior, LN Rusche, M Bryk, M Bühler, M Dubarry, M Paschini, M Van het Hoog, MA Pfaller, MD De Backer, MJ McEachern, N Saksouk, PA Dumesic, PR Lephart, PR Lephart, R Kaur, RB Wilson, RJ Bennett, S Greiss, S Henikoff, S Imai, S Kueng, S Rea, SI Iwaguchi, T Jones, T Kobayashi, T Kobayashi, T Kouzarides, VM Bruno, W Shou, WS Chu, X Bi   +56 more
core   +1 more source

Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila.

PLoS Genetics, 2005
Heterochromatin comprises a significant component of many eukaryotic genomes. In comparison to euchromatin, heterochromatin is gene poor, transposon rich, and late replicating.
Danielle Vermaak, Steven Henikoff, Harmit S Malik   +2 more
doaj   +2 more sources

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. [PDF]

, 2020
Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Acevedo, David, Beliveau, Brian, Cavalli, Giacomo, KARPEN, Gary H., Lee, Yuh, Martins, Nuno, Ogiyama, Yuki, Wu, C-Ting   +7 more
core   +3 more sources

Specificity, propagation, and memory of pericentric heterochromatin

Molecular Systems Biology, 2014
The cell establishes heritable patterns of active and silenced chromatin via interacting factors that set, remove, and read epigenetic marks. To understand how the underlying networks operate, we have dissected transcriptional silencing in pericentric ...
Katharina Müller‐Ott, Fabian Erdel, Anna Matveeva, Jan‐Philipp Mallm, Anne Rademacher, Matthias Hahn, Caroline Bauer, Qin Zhang, Sabine Kaltofen, Gunnar Schotta, Thomas Höfer, Karsten Rippe   +11 more
doaj   +1 more source

Transcription of satellite DNAs in insects [PDF]

, 2011
Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic, FELICIELLO, ISIDORO, J. Brajkovic, Z. Pezer   +3 more
core   +1 more source

Heterochromatin protein 1 (HP1a) positively regulates euchromatic gene expression through RNA transcript association and interaction with hnRNPs in Drosophila. [PDF]

PLoS Genetics, 2009
Heterochromatin Protein 1 (HP1a) is a well-known conserved protein involved in heterochromatin formation and gene silencing in different species including humans.
Lucia Piacentini, Laura Fanti, Rodolfo Negri, Valerio Del Vescovo, Alessandro Fatica, Fabio Altieri, Sergio Pimpinelli   +6 more
doaj   +1 more source

An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin

Journal of Cell Science, 1997
ABSTRACT The actin-related proteins have been identified by virtue of their sequence similarity to actin. While their structures are thought to be closely homologous to actin, they exhibit a far greater range of functional diversity. We have localized the Drosophila actin-related protein, Arp4, to the nucleus.
Frankel, S, Sigel, E, Craig, C, Elgin, Sarah C.R., Mooseker, M, Artavanis-Tsakonas, S   +5 more
openaire   +3 more sources