Results 151 to 160 of about 92,883 (234)

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

Synthesis, Characterization, Antimicrobial and Anticancer Evaluation of Novel Heterocyclic Diazene Compounds Derived from 8-Quinolinol. [PDF]

Pharmaceuticals (Basel)
Burcă I, Diaconescu AM, Badea V, Péter F.   +3 more
europepmc   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Thienopyrimidine scaffolds as promising antimicrobial agents: synthesis, biological evaluation, DFT analysis and molecular docking. [PDF]

RSC Adv
Sayed M, Naguib MA, Mohammed AAK, Hassanien R, Tolba MS, Ahmed M.   +5 more
europepmc   +1 more source

Metal‐Free Covalent Organic Frameworks for Photocatalytic CO2 Reduction

ChemistryEurope, EarlyView.
This review presents an environmentally sustainable strategy to address the critical issue of escalating atmospheric CO2 levels. It explores the application of metal‐free covalent organic frameworks in a photocatalytic approach, offering a green and efficient strategy for carbon dioxide reduction and contributing to climate change mitigation.
Supriti Dutta, Akhtar Alam, Pekham Chakrabortty, Pradip Pachfule   +3 more
wiley   +1 more source

Total synthesis of natural products based on hydrogenation of aromatic rings. [PDF]

Beilstein J Org Chem
Wu H, Qi X.
europepmc   +1 more source

Synthesis and Characterization of π‐Extended Azulenes via Nucleophilic Substitution and Intramolecular Cyclization of 5‐Alkynyl‐6‐Fluoroazulenes

ChemistryEurope, EarlyView.
A modular synthetic approach enables the preparation of azulene‐fused heterocycles via nucleophilic aromatic substitution followed by intramolecular cyclization of alkynyl fluoroazulenes. The method allows the incorporation of various heteroatoms (N, O, S, Se, and Te), leading to structurally diverse heteroannulated azulenes.
Martin C. Dietl, Matthias Scherr, Christopher Hüßler, Henrik T. Habeck, Carmen L. M. Henel, Jürgen Graf, Frank Rominger, Matthias Rudolph, A. Stephen K. Hashmi   +8 more
wiley   +1 more source

Discovery of novel progesterone-heterocyclic conjugates and their encapsulated polymeric nanoparticles as potential CDK8 inhibitors: lung cytotoxicity evaluation, gene expression, and molecular docking. [PDF]

RSC Med Chem
Omar YY, Elmasry GF, El-Kady DS, Abd-Rabou AA, El-Moghazy SM, Awadallah FM, Elmegeed GA, Elsayed GH.   +7 more
europepmc   +1 more source

Easier, Safer, and Greener: Unlocking the Power of Solid Reagents in Organic Reactions by Mechanochemistry

ChemistryEurope, EarlyView.
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego, Nicolas Pétry, Julien Pinaud, Olivia Giani, Frédéric Lamaty   +4 more
wiley   +1 more source

Chiral hypervalent iodine catalyzed stereoselective skeletal editing of pyrimidine fused heterocycles. [PDF]

Nat Commun
Sun WW, Xie YB, Wu B.
europepmc   +1 more source