Results 151 to 160 of about 132,796 (171)

Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.

Journal of Medicinal Chemistry, 1995
In view of the selective anti-HSV activity of 1,5-anhydro-2,3-dideoxy-2- (5-iodouracil-1-yl)-D-arabino-hexitol, a series of novel 1,5-anhydrohexitol nucleosides were synthesized and evaluated for their inhibitory activity against several viruses.
I. Verheggen, A. Van Aerschot, L. Van Meervelt, J. Rozenski, L. Wiebe, R. Snoeck, G. Andrei, J. Balzarini, P. Claes, E. De Clercq   +9 more
semanticscholar   +1 more source

Über Germanium‐haltige Heterocyclen, I. Darstellung und Charakterisierung der 8‐Ring‐Verbindungen 2,2‐Dichlor‐1,3,6,2‐trithiagermocan und 5,5‐Dichlor‐1,4,6,5‐oxadithiagermocan

, 1975
Die Darstellung der Titelverbindungen 3 und 4 wird beschrieben. 1H-NMR-, IR-, Raman- und Massenspektren werden zusammen mit den entsprechenden Spektren der analogen Zinnverbindungen 1 und 2 diskutiert.
M. Dräger, L. Ross
semanticscholar   +1 more source

Bicyclic 6 + 6 Systems: Advances in the Chemistry of Heterocyclic Compounds Incorporated Pyrimido[1,2-a]Pyrimidine Skeleton

Mini-Reviews in Organic Chemistry, 2020
The present review has highlighted the chemistry of pyrimido[1,2-a]pyrimidine compounds as one of the most important classes of heterocyclic systems.
M. Monier, D. Abdel-Latif, A. El‐Mekabaty, K. Elattar   +3 more
semanticscholar   +1 more source

Dissociative electron attachment induced ring opening in five-membered heterocyclic compounds.

Physical Chemistry, Chemical Physics - PCCP, 2018
Five-membered heterocyclic structures, which exist widely in biological systems and play an active role in various biochemical processes, have been studied extensively from a fundamental perspective.
Zhou Li, I. Carmichael, S. Ptasińska
semanticscholar   +1 more source

An Efficient Synthesis of Some New Azaspirocycloalkane Derivatives from 1-anilinocycloalkanecarboxamide

, 2014
1-anilinocyclohexanecarboxamides 2a-c were found to be a versatile precursors for the synthesis of five-, six- and seven-membered ring spiroheterocycles compounds 3-14.
M. Mohamed, H. M. Moustafa, M. A. El‐Remaily   +2 more
semanticscholar   +1 more source

Synthesis, α-amylase inhibitory activity evaluation and in silico molecular docking study of some new phosphoramidates containing heterocyclic ring

, 2020
We have synthesized a series of phosphoramidates containing a heterocyclic moiety with good yields (88–95%) by the reaction of (E)-5-benzylidene-3-((2-hydroxyethoxy)methyl)thiazolidine-2,4-dione with ethyl phosphorodichloridate followed by the reaction ...
Sk. Md. Altaff, T. Raja Rajeswari, Ch. Subramanyam   +2 more
semanticscholar   +1 more source

Cycloadditionen von Benzothiet und aromatischen Nitroso‐Verbindungen

, 1993
Cycloaddition Reactions of Benzothiete and Aromatic Nitroso Compounds The new heterocyclic ring systems 4H-3,1,2-benzoxathiazines 4 and 2,3-dihydro-1,2-benzothiazol 1-oxides 6 can be synthesized by cycloaddition of benzothiete (1) and aromatic ...
K. Saul, H.‐L. Eckes, H. Meier, D. Jacob   +3 more
semanticscholar   +1 more source

N-Heterocyclic Olefin Catalysis for the Ring Opening of Cyclic Amidine Compounds: A Pathway to the Synthesis of ε-Caprolactam- and γ-Lactam-Derived Amines.

Journal of Organic Chemistry, 2019
For the first time, 1,2-dimethyl-3-ethylimidazolium iodide (1a) catalyzes the ring opening of the bicyclic amidine system of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) or DBN (1,5-diazabicyclo[4.3.0]non-5-ene) on reaction with aldehydes. The mechanism here
Daniela Peixoto, Gabriela Malta, Hugo Cruz, S. Barroso, A. Carvalho, L. Ferreira, P. Branco   +6 more
semanticscholar   +1 more source

Synthesis, Characterization and i n vi tro Cytotoxic Evaluation of Some Novel Heterocyclic Compounds Bearing the Indole Ring

, 2016
Reactions of 1H-indole-3-carboxaldhyde 1 with thiosemicarbazide derivatives give thiosemicarbazone derivatives 2a,b. Cyclization of thiosemicarbazone 2a with HCl, Ac2O, phenacyl bromides and chloroacetic acid afforded the corresponding 1,2,4-triazole-3 ...
A. Salman, N. A. Mahmoud, M. Mohamed, A. Abdel‐Aziem, Doaa M Elsisi   +4 more
semanticscholar   +1 more source

Tautomerism-dependent ring construction of N-heterocyclic compounds from the reactions of 1-alkynyl Fischer carbene complexes and substituted pyrazolinones.

Journal of Organic Chemistry, 2006
Four types of N-heterocyclic ring systems were successfully constructed from the reactions of 1-alkynyl Fischer carbene complexes (OC)5M=C(OEt)C[triple bond]CPh (1) (M = Cr, W) and substituted pyrazolinones (2). Reactions of 1 with 3-methyl-2-pyrazolin-5-
Zhaoyan Zheng, Zhengkun Yu, N. Luo, Xiuwen Han   +3 more
semanticscholar   +1 more source