Results 251 to 260 of about 23,910,082 (307)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

scEWE: high-order element-wise weighted ensemble clustering for heterogeneity analysis of single-cell RNA-sequencing data. [PDF]

Brief Bioinform
Huang Y, Jiang H, Ching WK.
europepmc   +1 more source

Spatial stratified heterogeneity analysis of field scale permafrost in Northeast China based on optimal parameters-based geographical detector. [PDF]

PLoS One
Guo Y, Liu S, Qiu L, Zhang C, Shan W.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Quantifying heterogeneity in a meta-analysis

Statistics in Medicine, 2002
AbstractThe extent of heterogeneity in a meta‐analysis partly determines the difficulty in drawing overall conclusions. This extent may be measured by estimating a between‐study variance, but interpretation is then specific to a particular treatment effect metric. A test for the existence of heterogeneity exists, but depends on the number of studies in
Simon G Thompson, Julian Higgins
exaly   +3 more sources

An Analysis of the Heterogeneity of Albumin

Preparative Biochemistry, 1980
A simple and rapid procedure for characterization of serum albumin samples and for the isolation of fractions from fresh serum or commercial sources has been developed, based on DEAE Sepharose CL-6B ion exchange chromatography. Characterization of the fractions included sulfhydryl analysis, gel electrophoresis, and immunoelectrophoresis.
J, Janatova, R E, Crandall, J D, Andrade
openaire   +2 more sources

Minifrac Analysis For Heterogeneous Reservoirs

Annual Technical Meeting, 1990
Abstract General minifrac analysis type curves for analysis of heterogeneous formations have been developed and are presented in this paper. These type curves apply to a wide variety of formations including coal beds and naturally fractured formations. The new type curves have been developed for the Perkins and Kern
M.Y. Soliman, R.D. Kuhlman, D.K. Poulsen
openaire   +1 more source