Results 81 to 90 of about 785,223 (333)

Predição de valores genéticos utilizando inferência bayesiana e frequentista em dados simulados = Prediction of genetic values using bayesian inference and frequent on simulated data

Acta Scientiarum: Animal Sciences, 2010
Dados simulados foram utilizados para comparar as metodologias Eblup eBayesiana, em dados com homogeneidade de variâncias, heterogeneidade de variância genética e heterogeneidade de variância genética e ambiental.
José Marques Carneiro Júnior, Giselle Mariano Lessa de Assis, Ricardo Frederico Euclydes, Williane Maria de Oliveira Martins, Priscila Ferreira Wolter   +4 more
doaj  

Variance component and breeding value estimation for genetic heterogeneity of residual variance in Swedish Holstein dairy cattle.

Journal of Dairy Science, 2013
Trait uniformity, or micro-environmental sensitivity, may be studied through individual differences in residual variance. These differences appear to be heritable, and the need exists, therefore, to fit models to predict breeding values explaining ...
Lars Rönnegård, Lars Rönnegård, M. Felleki, M. Felleki, W. Fikse, H. A. Mulder, Erling Strandberg   +6 more
semanticscholar   +1 more source

Absorptive capacity and the growth and investment effects of regional transfers : a regression discontinuity design with heterogeneous treatment effects [PDF]

, 2012
Researchers often estimate average treatment effects of programs without investigating heterogeneity across units. Yet, individuals, firms, regions, or countries vary in their ability, e.g., to utilize transfers.
Becker, Sascha O., Egger, Peter, Ehrlich, Maximilian von   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

A pluralistic framework for measuring, interpreting and decomposing heterogeneity in meta‐analysis

Methods in Ecology and Evolution
Measuring heterogeneity, or inconsistency, among effect sizes is a crucial step for interpreting meta‐analytic evidence across diverse taxonomic groups and spatiotemporal contexts.
Yefeng Yang, Daniel W. A. Noble, Rebecca Spake, Alistair M. Senior, Malgorzata Lagisz, Shinichi Nakagawa   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Efficient GMM Estimation of Dynamic Panel Data Models Where Large Heterogeneity May Be Present [PDF]

This paper addresses the many instruments problem, i.e. (1) the trade-off between the bias and the efficiency of the GMM estimator, and (2) inaccuracy of inference, in dynamic panel data models where unobservable heterogeneity may be large.
Kazuhiko Hayakawa
core  

Panel Data Models with Nonadditive Unobserved Heterogeneity: Estimation and Inference [PDF]

, 2013
This paper considers fixed effects estimation and inference in linear and nonlinear panel data models with random coefficients and endogenous regressors.
Fernandez-Val, Ivan, Lee, Joonhwah
core   +2 more sources

Estimation of Heterogeneous Variances Using Empirical Bayes Methods: Theoretical Considerations

Journal of Dairy Science, 1992
Procedures are described to estimate variances when heterogeneity of genetic and residual dispersion parameters exists for some criterion. Genetic and residual variances are considered to follow distributions with either known or unknown parameters. The estimates of variances obtained are weighted averages of the corresponding parameter and of a data ...
Gianola, Daniel, Foulley, Jean Louis, J. L., Fernando, R.L., Henderson, C.R., Weigel, A.   +4 more
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source