Results 131 to 140 of about 1,365,709 (331)
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Progressive Taxation, Wealth Distribution, and Macroeconomic Stability [PDF]
Using the standard neoclassical growth model with two types of agents, we examine how the presence of heterogenous agents affects the stabilization role of progressive income taxation.
Kazuo Mino, Yasuhiro Nakamoto
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Weird Ties? Growth, Cycles and Firm Dynamics in an Agent-Based Model with Financial-Market Imperfections [PDF]
This paper studies how the interplay between technological shocks and financial variables shapes the properties of macroeconomic dynamics. Most of the existing literature has based the analysis of aggregate macroeconomic regularities on the ...
Domenico Delli Gatti +3 more
core
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Estimation of financial agent-based models with simulated maximum likelihood
, 2016 This paper proposes a general computational framework for empirical estimation of financial agent based models, for which criterion functions do not have known analytical form.
Barunik, Jozef, Kukacka, Jiri
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Improving Reinforcement Learning Experiments in Unity through Waypoint Utilization
Proceedings of the International Florida Artificial Intelligence Research Society ConferenceMulti-agent Reinforcement Learning (MARL) models teams of agents that learn by dynamically interacting with an environment and each other, presenting opportunities to train adaptive models for team-based scenarios.
Caleb Koresh +3 more
doaj +1 more source
On payoff heterogeneity in games with strategic complementarities [PDF]
Payoff heterogeneity weakens positive feedback in binary choice models in two ways. First, heterogeneity drives individuals to corners where they are unaffected by strategic complementarities.
Antonio Ciccone, James Costain
core
Essays on heterogeneous agent models
, 2015 There is a continued interest among economists on the interconnections between financial markets, credit markets and the real economy. The three main chapters of this dissertation contribute to the understanding of how financial and credit frictions - either at the fi rm or household level - can aff ect the real economy, and even trigger
openaire +2 more sources