Results 51 to 60 of about 275,178 (260)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Updating Wealth in an Asset Pricing Model with Heterogeneous Agents

Discrete Dynamics in Nature and Society, 2010
We consider an asset-pricing model with wealth dynamics in a market populated by heterogeneous agents. By assuming that all agents belonging to the same group agree to share their wealth whenever an agent joins the group (or leaves it), we develop an ...
Serena Brianzoni, Cristiana Mammana, Elisabetta Michetti   +2 more
doaj   +1 more source

Estimation of potential field environments from heterogeneous behaviour of sensing agents

IET Signal Processing, 2023
This paper proposes a novel modelling framework for estimating the global potential field from trajectories of multiple sensing agents whose perception of the unknown field is subject to abrupt changes.
Anastasia Kadochnikova, Visakan Kadirkamanathan   +1 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Learning Stability in Economics with Heterogenous Agents [PDF]

SSRN Electronic Journal, 2002
Abstract An economy exhibits structural heterogeneity when the forecasts of different agents have different effects on the determination of aggregate variables. We study the important case of economies in which agents' behavior depends on forecasts of aggregate variables and show how different forms of heterogeneity in structure, forecasts, and ...
Honkapohja, Seppo, Mitra, Kaushik
openaire   +5 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Authentication Scheme Based on Agents for Heterogeneous Cloud

Dianxin kexue, 2013
Considering the comp1exity of dep1oying network nodes, 1arge amount of ca1cu1ation and frequent mutua1 messages for heterogeneous c1oud, two service patterns, i.e.authentication agent and service agent were proposed, A1so, the proxy digita1 signature ...
Jiwen Guo, Xianwei Zhou
doaj   +2 more sources

Heterogeneous-Agent Reinforcement Learning

, 2023
The necessity for cooperation among intelligent machines has popularised cooperative multi-agent reinforcement learning (MARL) in AI research. However, many research endeavours heavily rely on parameter sharing among agents, which confines them to only homogeneous-agent setting and leads to training instability and lack of convergence guarantees.
Zhong, Yifan, Kuba, Jakub Grudzien, Feng, Xidong, Hu, Siyi, Ji, Jiaming, Yang, Yaodong   +5 more
openaire   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Dynamic Path Planning Algorithm for Heterogeneous Groups in Aircraft Carrier Aviation SupportOperations [PDF]

Jisuanji kexue
The path planning task in aircraft carrier support operation has the problem of high dynamic scene and strong heterogeneity of agents.Although the traditional global path planning algorithm can obtain the global optimal results,it can not adapt to the ...
SUN Didi, LI Chaochao
doaj   +1 more source