Effect of catalytic conditions on the synthesis of new aconitate esters [PDF]
Sugar cane is a crop which generates large amounts of biomass and a juice rich in highvalue natural molecules. After extracting sugar from the juice, the recovering of various compounds such as organic acids contained in molasses could contribute to ...
Hoareau, William +4 more
core +3 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Understanding a Heterogeneous Catalyst in Action
The role of catalysis in the clean production of energy and chemicals will become increasingly important and new catalysts must be developed.
Jeroen A. van Bokhoven +2 more
doaj +1 more source
Morphology of supported polymer electrolyte ultra-thin films: a numerical study
Morphology of polymer electrolytes membranes (PEM), e.g., Nafion, inside PEM fuel cell catalyst layers has significant impact on the electrochemical activity and transport phenomena that determine cell performance.
Abraham F. F. +102 more
core +5 more sources
Polyoxometalate (POM)-layered double hydroxides (LDH) composite materials: design and catalytic applications [PDF]
Layered double hydroxides (LDHs) are an important large class of two-dimensional (2D) anionic lamellar materials that possess flexible modular structure, facile exchangeability of inter-lamellar guest anions and uniform distribution of metal cations in ...
Li, Tengfei +2 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Microwave assisted synthesis of 1-substituted-1H-tetrazoles was developed using zinc sulfide nanoparticles as heterogeneous catalyst under solvent free conditions.
Hossein Naeimi +2 more
doaj +1 more source
Determination of Reaction Kinetics of Heterogeneous Decomposition of Hydrazine with Nickel Catalyst Based on Gamma-Alumina [PDF]
In this research, an adiabatic fixed bed reactor is used to determine the reaction kinetics of the heterogeneous decomposition of hydrazine and ammonia with a 15% nickel catalyst based on gamma alumina.
Hosein Ebrahim +2 more
doaj +1 more source
In situ surface coverage analysis of RuO2-catalysed HCl oxidation reveals the entropic origin of compensation in heterogeneous catalysis [PDF]
In heterogeneous catalysis, rates with Arrhenius-like temperature dependence are ubiquitous. Compensation phenomena, which arise from the linear correlation between the apparent activation energy and the logarithm of the apparent pre-exponential factor ...
Farra, R. +10 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source

