Results 121 to 130 of about 98,405 (300)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A New Paradigm for Proactive Self-Healing in Future Self-Organizing Mobile Cellular Networks [PDF]
, 2018 Mobile cellular network operators spend nearly a quarter of their revenue on network management and maintenance. Remarkably, a significant proportion of that budget is spent on resolving outages that degrade or disrupt cellular services.
Asghar, Ahmad
core
Channel Management in Heterogeneous Cellular Networks [PDF]
, 2007 Motivated by the need to increase system capacity in the face of tight FCC regulations, modem cellular systems are under constant pressure to increase the sharing of the frequency spectrum among the users of the network. Key to increasing system capacity
Arbabi, Mohammad Hadi
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A New Distributive Approach for Achieving Timing Synchronization in Heterogenous Networks, (in peer review) [PDF]
, 2010 Heterogeneous networks have the potential to improve coverage, throughput, and energy efficiency of wireless networks through the use of specialized cellular structures, i.e., femtocells and macrocells.
Mehrpouyan, Hani, +2 more
core
Large-Scale Spatial Distribution Identification of Base Stations in Cellular Networks
IEEE Access, 2015 The performance of cellular system significantly depends on its network topology, while cellular networks are undergoing a heterogeneous evolution. This promising trend introduces the unplanned deployment of smaller base stations (BSs), thus complicating
Yifan Zhou +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Energy-Throughput Tradeoffs in Cellular/WiFi Heterogeneous Networks with Traffic Splitting [PDF]
, 2018 Heterogeneous networks are expected to play a major role towards meeting the exploding traffic demand over cellular systems. Particularly, existing WiFi hotspots will be dynamically utilized to offload the traffic of cellular mobile subscribers.
Hajj, Hazem +3 more
core +1 more source
IEEE Access, 2017 Full-duplex (FD) technology is currently under consideration for adoption in a range of legacy communications standards due to its attractive features. On the other hand, cellular networks are becoming increasingly heterogeneous as operators deploy a mix
Mhd Omar Al-Kadri +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source