Results 101 to 110 of about 4,599,562 (265)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Evolutionary cellular configurations for designing feed-forward neural networks architectures [PDF]

, 2001
Proceeding of: 6th International Work-Conference on Artificial and Natural Neural Networks, IWANN 2001 Granada, Spain, June 13–15, 2001In the recent years, the interest to develop automatic methods to determine appropriate architectures of feed-forward ...
Gutiérrez Sánchez, Germán, Molina López, José Manuel, Galván, Inés M., Sanchis de Miguel, María Araceli, Isasi, Pedro, Galván León, Inés María, Isasi Viñuela, Pedro   +6 more
core   +1 more source

Large-Scale Spatial Distribution Identification of Base Stations in Cellular Networks

IEEE Access, 2015
The performance of cellular system significantly depends on its network topology, while cellular networks are undergoing a heterogeneous evolution. This promising trend introduces the unplanned deployment of smaller base stations (BSs), thus complicating
Yifan Zhou, Zhifeng Zhao, Yves Louet, Qianlan Ying, Rongpeng Li, Xuan Zhou, Xianfu Chen, Honggang Zhang   +7 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Wireless Cellular Networks

, 2010
When aiming for achieving high spectral efficiency in wireless cellular networks, cochannel interference (CCI) becomes the dominant performancelimiting factor.
Rong Zhang, Zhang, Rong, Hanzo, Lajos, Lajos Hanzo   +3 more
core   +2 more sources

Full-Duplex Small Cells for Next Generation Heterogeneous Cellular Networks: A Case Study of Outage and Rate Coverage Analysis

IEEE Access, 2017
Full-duplex (FD) technology is currently under consideration for adoption in a range of legacy communications standards due to its attractive features. On the other hand, cellular networks are becoming increasingly heterogeneous as operators deploy a mix
Mhd Omar Al-Kadri, Yansha Deng, Adnan Aijaz, Arumugam Nallanathan   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

TinyIBE: identity-based encryption for heterogeneous sensor networks [PDF]

, 2009
The area of security for heterogeneous sensor networks (HSNs) is still an open research field that requires new cryptographic solutions. Recent results have demonstrated that elliptic curve cryptography (ECC) and pairing-based cryptography (PBC) are ...
Martin Collier, Collier, Martin, Piotr Szczechowiak, Szczechowiak, Piotr   +3 more
core   +2 more sources

An ASAPPP Approach to the Spectrum Allocation in General Heterogeneous Cellular Networks

IEEE Access, 2019
The increasing heterogeneity of cellular networks makes the signal-to-interference-ratio (SIR) distribution challenging to derive, which restricts the further analysis of metrics that depend on it.
Haichao Wei, Na Deng, Martin Haenggi
doaj   +1 more source