Results 91 to 100 of about 4,599,562 (265)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Deep Q-Network-Based Algorithm for Multi-Connectivity Optimization in Heterogeneous Cellular-Networks. [PDF]
Sensors (Basel), 2022 Hernández-Carlón JJ +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
IEEE Access, 2018 Resource allocation in secure communication is of primary importance due to the fact that the next-generation wireless network (5G) aims to achieve high spectral efficiency and a high level of security.
Bing Wang +5 more
doaj +1 more source
A Dynamic Algorithm for Interference Management in D2D-Enabled Heterogeneous Cellular Networks: Modeling and Analysis. [PDF]
Sensors (Basel), 2022 Kamruzzaman M, Sarkar NI, Gutierrez J.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Green Base Station Assignment for NOMA-Enabled HCNs
IEEE Access, 2019 In this paper, for the heterogeneous cellular networks (HCNs) with non-orthogonal multiple access (NOMA), we mainly concentrate on the design of green base station (BS) assignment integrating with power allocation.
Tianqing Zhou +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Equilibrium analysis of cellular neural networks [PDF]
, 2004 Cellular neural networks are dynamical systems, described by a large set of coupled nonlinear differential equations. The equilibrium point analysis is an important step for understanding the global dynamics and for providing design rules. We yield a set
Checco, P. +3 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source