Results 121 to 130 of about 27,386 (301)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Heterogeneity and Female-Headed Households in Sri Lanka: Vulnerability and Resilience in a Transitional Development Society

open access: yes, 2014
Since the 1970s, female-headed households (FHHs) in developing countries have often been used in development literature as a proxy for poverty and vulnerability.
Adikaram Boyagoda, Adikaram Mudiyanselage Kumudika Suramya
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Trade Liberalization and Heterogeneous Time Preference across Countries: A Possibility of Trade Deficits with China [PDF]

open access: yes
Strategies for trade liberalization in developing countries when time preference rates are heterogeneous across countries are examined in the context of endogenous growth.
Taiji Harashima
core  

Essays on macroeconomics and household heterogeneity

open access: yes, 2018
The goal of this thesis is to explore how household heterogeneity propagates and amplifies macroeconomic shocks within the economy using both economic theory and empirical data. The assumption of a single "representative" household has been a mainstay of macroeconomic research over the past half-century.
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The role of rural off-farm employment in agricultural development among farm households in low-income countries: Evidence from Zimbabwe

open access: yes
This study examines the widely held view that earnings from rural wage employment can help farm households overcome constraints on farm investments.
Chikwama, Cornilius
core  

On the Distributional Effects of Reducing Capital Taxes (previously: Factor Taxation with Heterogeneous Agents) [PDF]

open access: yes
We investigate the welfare implications of changing the mix between capital and labor taxes for a model economy in which heterogeneous households face uninsurable labor income risk.
Jonathan Heathcote
core  

Urban-rural equalization of basic public services, fertility behavior and growth

open access: yesInternational Review of Economics & Finance
The equalization of basic public services is a central reform priority in China. This study develops a three-period overlapping generations (OLG) model with heterogeneous agents to examine how urban-rural equalization in pension subsidies and public ...
Ning Zhang, Yue Ding
doaj   +1 more source

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