Results 51 to 60 of about 27,386 (301)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Impact of India’s farm science centers (Krishi Vigyan Kendras) on farm households’ economic welfare: An evidence from a national farmers’ survey

The Indian Journal of Agricultural Sciences
This study examines the impact of access to India’s farm science centers (Krishi Vigyan Kendras, or KVKs) on agricultural households’ welfare using household data from the nationally representative Situation Assessment Survey of Agricultural Households ...
ANJANI KUMAR, A K MISHRA, A K SINGH, SUNIL SAROJ, MISHA MADHAVAN M, P K JOSHI   +5 more
doaj   +1 more source

A double hurdle estimation of crop diversification decisions by smallholder wheat farmers in Sinana District, Bale Zone, Ethiopia

CABI Agriculture and Bioscience, 2022
Background Ethiopia is heterogeneous in agro-ecological, social, and economic conditions. In such heterogeneous environment, crop production needs to be diversified to meet household consumption and market needs.
Dereje Derso, Degefa Tolossa, Abrham Seyoum   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The uncertainty-driven channel of monetary transmission on household consumption: the role of households’ balance sheet positions

International Review of Economics & Finance
We investigate the combined effects of contractionary monetary policy shocks and policy uncertainty on household consumption behavior. Monetary tightening policies are associated with high uncertainty in the macroeconomy, which can exacerbate their ...
Pragati Priya, Chandan Sharma
doaj   +1 more source

Heterogeneous Credit Impacts on Health Care Spending of the Poor in Peri-Urban Areas, Vietnam

SAGE Open, 2016
Quantile treatment effects are estimated to study the impacts of household credit access on health spending by poor households in one District of Ho Chi Minh City, Vietnam.
Tinh Thanh Doan, Gibson John, Tuyen Quang Tran   +2 more
doaj   +1 more source

Housing choice structure: examples of two different-size cities from Turkey

International Journal of Strategic Property Management, 2015
The distribution pattern of housing in any urban area will be extremely diverse and heterogeneous. The shape of this pattern depends on intrinsic properties of the housing units themselves as well as on accessibility, environmental quality and the ...
Elif Alkay
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

NONLINEAR PROGRESSIVE INCOME TAXATION AND INEQUALITIES IN INCOME AND WEALTH BETWEEN HETEROGENEOUS HOUSEHOLDS [PDF]

Buletin ştiinţific: Universitatea din Piteşti. Seria Ştiinţe Economice, 2018
This paper constructs a dynamic economic growth model in an integrated Walrasian and neoclassical equilibrium theory. This study is concerned with dynamic interactions between progressive nonlinear taxation and wealth and income distributions between ...
Wei-Bin ZHANG
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source