Results 71 to 80 of about 23,495 (217)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The influence of external finance and domestic investment on clean energy transitions for African urban and rural households

open access: yesDiscover Sustainability
This study examines the determinants of household energy transition in 48 African countries (2000–2023), focusing on domestic investment and external finance roles.
Gildas Dohba Dinga, Gisele Mah
doaj   +1 more source

Transmission mechanisms in behavioral macroeconomic models

open access: yesInternational Review of Economics & Finance
This paper reassesses monetary policy transmission in a tractable TANK-based New Keynesian setting with hand-to-mouth households and animal spirits. In the model, animal spirits are introduced through behavioral wage expectations: perceived macroeconomic
Xin Xu
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Development of a territory-wide household-based composite index for measuring relative distribution of households by economic status in individual small areas throughout Hong Kong

open access: yesBMC Public Health
Background Many countries have developed their country/nation-wide multidimensional area-based index on deprivation or socioeconomic status for resource allocation, service planning and research.
Eva L.H. Tsui   +10 more
doaj   +1 more source

Modelling Consumer Demand in Intermittent Water Supply (IWS) Networks: Evidence from Nepal

open access: yesEngineering Proceedings
Modelling consumer demand under intermittent water supply (IWS) is an unresolved challenge. To understand withdrawal behaviours in more detail, fifty-six smart meters were installed in households across an IWS network in Lahan, Nepal.
Matthew MacRorie   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

How Do Livelihood Assets Affect Subjective Well-Being Under Different Livelihood Strategies? Evidence from Tibetan Rural Households in China

open access: yesAgriculture
Evaluating rural households’ subjective well-being (SWB) and identifying its determinants is crucial for rural sustainable development. This study takes Diqing Prefecture in the Tibetan region of China as a case, aiming to address two key research ...
Di Lei   +4 more
doaj   +1 more source

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