Results 51 to 60 of about 8,083,020 (307)

Network resource control for data intensive applications in heterogeneous infrastructures

open access: yes, 2012
Many scientific workflow applications are data intensive. Large quantities of simulation generated data or data collected from sensors or instruments drive the process flow of the applications, and the processing of the data is commonly done at a ...
Cosmin Dumitru   +8 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

An intelligent radio access network selection and optimisation system in heterogeneous communication environments

open access: yes, 2010
PhDThe overlapping of the different wireless network technologies creates heterogeneous communication environments. Future mobile communication system considers the technological and operational services of heterogeneous communication environments. Based
Luo, Weizhi
core  

An iteration method for identifying yeast essential proteins from heterogeneous network

open access: yesBMC Bioinformatics, 2019
Essential proteins are distinctly important for an organism’s survival and development and crucial to disease analysis and drug design as well. Large-scale protein-protein interaction (PPI) data sets exist in Saccharomyces cerevisiae, which provides us ...
Bi-hai Zhao   +5 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Heterogeneous teaching evaluation network based offline course recommendation with graph learning and tensor factorization

open access: yes, 2020
Course recommendation systems are applied to help students with different needs select courses in a large range of course resources. However, a student’s needs are not always determined by their personal interests, they are also influenced by teachers ...
Shi, Kaize   +5 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Topology control in Heterogeneous Wireless Sensor Network

open access: yes, 2016
Topology of a Wireless Sensor Network determines the connectivity of the wireless network and topology Control is the important technique of extending network lifetime while preserving network connectivity.
Deshmukh, Prashant, Dandekar, Deepak R
core  

A QoS Aware Vertical Handover In Mobile Network

open access: yes, 2020
The convergence of heterogeneous wireless access technologies characterizes the 4G wireless networks. In such converged systems, the seamless and efficient handoff between different access technologies (vertical handoff) is essential and remains a ...
Khushboo, Kumari   +3 more
core   +1 more source

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