Results 61 to 70 of about 8,083,020 (307)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Enabling Heterogeneous Network Function Chaining
IEEE Transactions on Parallel and Distributed Systems, 2019 Today’s data center operators deploy network policies in both physical (e.g., middleboxes, switches) and virtualized (e.g., virtual machines on general purpose servers) network function boxes (NFBs), which reside in different points of the network, to ...
Lin Cui +5 more
semanticscholar +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Mobile Video Streaming over Heterogeneous Networks
, 2011 All-IP networks are under development with multimedia services in mind. Video multicast is an efficient way to deliver one video simultaneously to many users over such heterogeneous wired-to-wireless networks, such as in wireless IP applications where a ...
Salah M. Saleh Al-Majeed +5 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
HetNet: A Flexible Architecture for Heterogeneous Satellite-Terrestrial Networks
, 2021 As satellite networks have played an indispensable role in many fields, how to integrate them with terrestrial networks (e.g., the Internet) has attracted significant attention in academia.
Li, H +6 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Wireless Broadband Access: Policy Implications of Heterogeneous Networks [PDF]
A wireless heterogeneous network can help increase the access transmission speed and contribute thereby to the broadband deployment policies of administrations and telecommunications operators.
Rendon Schneir, Juan
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source