Results 91 to 100 of about 251,823 (301)

Heterologous biosynthesis of artemisinic acid in Saccharomyces cerevisiae

, 2016
Artemisinic acid is a precursor of antimalarial compound artemisinin. The titre of biosynthesis of artemisinic acid using Saccharomyces cerevisiae platform has been achieved up to 25 g l(-1); however, the performance of platform cells is still industrial
Wang, G, Li, X (reprint author), Chinese Acad Sci, Key Lab Environm & Appl Microbiol, Chengdu 610041, Peoples R China., Li, J, Li, X, Li, C   +4 more
core   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Heterologous Prime-Boost HIV-1 Vaccination Regimens in Pre-Clinical and Clinical Trials

Viruses, 2010
Currently, there are more than 30 million people infected with HIV-1 and thousands more are infected each day. Vaccination is the single most effective mechanism for prevention of viral disease, and after more than 25 years of research, one vaccine has ...
Julia L. Hurwitz, Patricia Flynn, Pamela Freiden, Nanna Howlett, Timothy D. Lockey, Kristen Branum, Karen S. Slobod, Bart G. Jones, Robert Sealy, Scott A. Brown, Sherri L. Surman   +10 more
doaj   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar, Laura Marti‐Sánchez, Loreto Martorell, Giorgia Dinoi, Antonio Vittorio Buono, Annamaria De Luca, Antonella Liantonio, Paola Imbrici   +7 more
wiley   +1 more source

Self‐Assembled Hybrid Cell‐Enzyme Materials for Gas‐Powered Biocatalysis

Advanced Functional Materials, EarlyView.
Integrating living cells with programmable enzyme networks enables hybrid materials that convert gaseous feedstocks into chemical reducing power. These gas‐powered catalytic beads operate as modular, recyclable platforms for adaptive biocatalysis and sustainable synthesis.
Marius Stoeckle, Kersten S. Rabe, Christof M. Niemeyer   +2 more
wiley   +1 more source

Autologous and Heterologous Minor and Major Bone Regeneration with Platelet-Derived Growth Factors

Journal of Functional Biomaterials
Aim: This review aims to explore the clinical applications, biological mechanisms, and potential benefits of concentrated growth factors (CGFs), autologous materials, and xenografts in bone regeneration, particularly in dental treatments such as alveolar
Gianna Dipalma, Angelo Michele Inchingolo, Valeria Colonna, Pierluigi Marotti, Claudio Carone, Laura Ferrante, Francesco Inchingolo, Andrea Palermo, Alessio Danilo Inchingolo   +8 more
doaj   +1 more source

The Ethics of Heterologous Ovarian Transplantation

, 2023
This project examines the ethical permissibility of heterologous ovarian transplantation to treat infertility, ovarian insufficiency, or both. Based on currently available data regarding the procedures’ risks, outcomes, and alternatives, it argues that ...
Brundage, Janetta
core  

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Characterization of the Serine Protease TlSP1 from Trichoderma longibrachiatum T6 and Its Function in the Control of Heterodera avenae in Wheat

Journal of Fungi
Serine protease is an extracellular protease secreted by biocontrol fungi that can effectively control nematode diseases by degrading nematode eggshells and enhancing plant resistance.
Xiujuan Wang, Shuwu Zhang, Bingliang Xu
doaj   +1 more source

Heterologous Prime-Boost Immunizations with a Virosomal and an Alphavirus Replicon Vaccine

, 2010
Heterologous prime-boost immunization strategies in general establish higher frequencies of antigen-specific T lymphocytes than homologous prime-boost protocols or single immunizations.
Pidder Jansen-Dürr, Annelies Riezebos-Brilman, Hoogeboom, Baukje-Nynke, Nijman, Hans W., Jansen-Duerr, Pidder, Riezebos-Brilman, Annelies, Daemen, Toos; id_orcid, Hans W. Nijman, Arjan de Mare, Jeroen T. Visser, Wilschut, Jan, Regts, Joke, Walczak, Mateusz, Jansen-Dürr, Pidder, Daemen, Toos, Marc Fiedler, Ate G. J. van der Zee, de Mare, Arjan, Toos Daemen, Fiedler, Marc, Walczakk, Mateusz, Jan Wilschut, van der Zee, Ate G. J., Mateusz Walczak, Visser, Jeroen T., Baukje-Nynke Hoogeboom, Joke Regts   +26 more
core   +1 more source