Results 231 to 240 of about 348,200 (357)

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

POTENTIATION OF THE LETHAL EFFECT OF ENDOTOXIN BY HETEROLOGOUS PLASMA [PDF]

open access: green, 1963
Fritz Karl Beller   +2 more
openalex   +1 more source

Comparative analysis of formyl peptide receptor 1 and formyl peptide receptor 2 reveals shared and preserved signalling profiles

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The pattern recognition receptors, formyl peptide receptors, FPR1 and FPR2, are G protein‐coupled receptors that recognize many different pathogen‐ and host‐derived ligands. While FPR1 conveys pro‐inflammatory signals, FPR2 is linked with pro‐resolving outcomes.
Denise Pajonczyk   +5 more
wiley   +1 more source

A 22 month prospective assessment of neutralizing and IgG antibody levels against SARS-CoV-2 variants following homologous and heterologous BNT162b2 boosting. [PDF]

open access: yesSci Rep
Mat Yassim AS   +11 more
europepmc   +1 more source

Survival of Heterologous Mammalian Implants*

open access: yesAnnals Of Surgery, 1960
Harvey B. Stone   +2 more
openaire   +4 more sources

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye   +5 more
wiley   +1 more source

Oviductin sets the species-specificity of the mammalian zona pellucida. [PDF]

open access: yesElife
de la Fuente D   +11 more
europepmc   +1 more source

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Proteolytic balance is dysregulated in many diseases, with proteases playing critical roles in pathological pathways. A high level of Trypsin‐3 expression has been implicated as a significant mediator of tumour progression and metastasis, and this protease is associated with poor prognosis for patients in various cancers.
Melissa David   +9 more
wiley   +1 more source

Immunogenicity and Safety of Heterologous Versus Homologous Prime-Boost Regimens With BBIBP-CorV and Ad26.COV2.S COVID-19 Vaccines: A Multicentric, Randomized, Observer-Blinded Non-inferiority Trial in Madagascar and Mozambique. [PDF]

open access: yesClin Infect Dis
Ramgi P   +39 more
europepmc   +1 more source

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