Results 211 to 220 of about 261,803 (304)

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source

Heterologous expression and characterization of synthetic polyester-degrading cutinases from <i>Fusarium</i> spp. in <i>Aspergillus niger</i>. [PDF]

Microbiol Spectr
Verschoor J-A, Arentshorst M, Regensburg-Tuink AJG, Seekles SJ, van den Hondel C, de Winde JH, Ram AFJ.   +6 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Heterologous expression of Arabidopsis FLS2 in Nicotiana benthamiana confers responsiveness to Ralstonia flg22 and activation of anti-bacterial immunity. [PDF]

Plant Biotechnol J
Li M, Chen Y, Wei Y, Macho AP.
europepmc   +1 more source

p75NTR Promotes Circadian‐Driven Mineralization During Tooth Development via CK2/PER2 Pathway

Cell Proliferation, EarlyView.
The diagram illustrates how the circadian rhythm regulates the p75NTR‐CK2‐PER2 axis, driving rhythmic biomineralisation during tooth development. ABSTRACT Circadian rhythm is an essential biological process that synchronises physiological activities with environmental light/dark cycles.
Manzhu Zhao, Hongyan Yuan, Di Wang, Meng Li, Bo Xie, Xuqiang Zou, Mingjie Lu, Ye Qiu, Jinlin Song   +8 more
wiley   +1 more source

Heterologous Expression of Bacteriocins from the Metagenome Mining of Cotija Cheese. [PDF]

Probiotics Antimicrob Proteins
Esquivel-López A, Rocha-Mendoza D, Serrano-Maldonado CE, Escobar-Zepeda A, Quirasco M.   +4 more
europepmc   +1 more source

WONOEP XVII appraisal: The immunopathogenesis of epilepsy

Epilepsia, EarlyView.
Abstract There is a wealth of data indicating that the immune system plays an important role in seizure disorders. This includes autoimmune encephalitis, in which an immune response directed against neuronal antigens results in brain inflammation and subsequent seizure activity, as well as autoimmune‐associated epilepsy and neuroinflammatory changes ...
Nihan Çarçak, Said Al Maawal, Peravina Thergarajan, Tracie H. L. Tan, Vinod Kumar Mehta, Tamara Baker, David C. Henshall, Aristea S. Galanopoulou, Özlem Akman, Pablo M. Casillas‐Espinosa, Raman Sankar, Laura Librizzi, Adam E. Handel   +12 more
wiley   +1 more source

Correction: A highly efficient heterologous expression platform to facilitate the production of microbial natural products in Streptomyces. [PDF]

Microb Cell Fact
Wang X, Lin P, Shen Q, Feng X, Xu S, Zhang Q, Liu Y, Ren C, Yong D, Duan Q, Huo L, Zhang Y, Li G, Fu J, Li R.   +14 more
europepmc   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Characterization of a β-Galactosidase from <i>Kosakonia oryzendophytica</i> and Its Heterologous Expression in <i>Bacillus subtilis</i> for Galactooligosaccharides Production. [PDF]

Molecules
Cheng Z, Jin X, Zhang Y, Ni D, Zhu Y, Xu W, Zhang W, Mu W.   +7 more
europepmc   +1 more source