Results 171 to 180 of about 700,500 (193)

Heterologous Prime–Boost Vaccinations for Poverty-Related Diseases: Advantages and Future Prospects

open access: yesExpert Review of Vaccines, 2009
Classical vaccination approaches, based on a single vaccine administered in a homologous prime-boost schedule and optimized to induce primarily neutralizing antibodies, are unlikely to be sufficiently efficacious to prevent TB, malaria or HIV infections. Novel vaccines, capable of inducing a more powerful immune response, in particular T-cell immunity,
Angelique Lemckert   +2 more
exaly   +3 more sources

Heterologous Prime-Boost Vaccination in Tumor Immunotherapy

2004
Most of the vaccine strategies under development use multiple immunizations with the same agent such as a viral vector encoding a tumor antigen. More recently, the concept of heterologous prime-boost immunization has been tested in animal models. This strategy involves the sequential administration of different delivery vectors encoding the same ...
Michael J. Palmowski, Caroline Smith
openaire   +1 more source

Comparison of Single, Homologous Prime-Boost and Heterologous Prime-Boost Immunization Strategies Against H5N1 Influenza Virus in a Mouse Challenge Model

Vaccine, 2010
Preparation for an H5N1 influenza pandemic in humans may involve priming the population with a vaccine produced from an existing, available H5N1 strain. We have used a mouse challenge model to compare the immunogenicity and efficacy of inactivated, Vero cell-derived, whole virus H5N1 vaccines in single immunization and homologous or heterologous prime ...
Nicolas Sabarth   +2 more
exaly   +3 more sources

Effect of homologous and heterologous prime–boost on the immune response to recombinant plague antigens

Vaccine, 2005
Among the pathogens that have been identified as potential agents of biological warfare or bioterrorism, Yersinia pestis is one of the main concerns due to the severity and potential transmissibility of the pneumonic form of the disease in humans. There are no approved vaccines for protection against pneumonic plague, but a Y.
Audrey, Glynn   +2 more
openaire   +2 more sources

Superior protection against paratuberculosis by a heterologous prime-boost immunization in a murine model

Vaccine
Vaccination is the best strategy to control Paratuberculosis (PTB), which is a significant disease in cattle and sheep. Previously we showed the humoral and cellular immune response induced by a novel vaccine candidate against PTB based on the Argentinian Mycobacterium avium subspecies paratuberculosis (Map) 6611 strain.
María Alejandra, Colombatti Olivieri   +11 more
openaire   +2 more sources

Heterologous prime-boost vaccine regimens against Chlamydia trachomatis

2014
Chlamydia trachomatis is the most common bacterial sexually transmitted disease in man and despite decades of effort, there is still no protective vaccine. Left untreated, genital infection can lead to pelvic inflammatory disease, ectopic pregnancy, and infertility. However, infection-induced immunity in both animal models and humans indicates a strong
openaire   +2 more sources

Heterologous Prime Boost Vaccine

2022
WOLLMANN GUIDO   +4 more
openaire   +2 more sources

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