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Heterologous Prime-Boost Vaccination with Inactivated Influenza Viruses Induces More Effective Cross-Protection than Homologous Repeat Vaccination

open access: yesVaccines, 2023
With concerns about the efficacy of repeat annual influenza vaccination, it is important to better understand the impact of priming vaccine immunity and develop an effective vaccination strategy. Here, we determined the impact of heterologous prime-boost
Noopur Bhatnagar   +2 more
exaly   +3 more sources

BNT162b2 COVID-19 vaccination in children alters cytokine responses to heterologous pathogens and Toll-like receptor agonists

open access: yesFrontiers in Immunology, 2023
BackgroundVaccines can have beneficial off-target (heterologous) effects that alter immune responses to, and protect against, unrelated infections. The heterologous effects of COVID-19 vaccines have not been investigated in children.AimTo investigate ...
Andres Noe   +2 more
exaly   +3 more sources

The acceptance to heterologous booster vaccination of COVID-19 vaccine among HCWs and targeted population: A cross-sectional study in central China

open access: yesFrontiers in Public Health, 2022
BackgroundThere are few studies reported on the acceptance of heterologous booster vaccination for the COVID-19 vaccine among healthcare workers (HCWs) and the general population. We aimed to address that gap and explore determinant factors of acceptance
Hong Su
exaly   +3 more sources

Safety and immunogenicity of heterologous ChAdOx1-nCoV19 and BNT162b2 vaccination: A meta-analysis of the heterologous COVID-19 vaccination outcomes

open access: yesVaccine, 2023
Here, we systematically assessed the safety and immunogenicity of the heterologous ChAd/BNT vaccination regimens.We evaluated the immunogenicity by the geometric mean titers ratio (GMTR) of the neutralizing antibody and anti-spike IgG. The safety of heterologous ChAd/BNT vaccination was evaluated using the pooled risk ratios (RRs) calculated by the ...
Yuxuan Hu
exaly   +3 more sources

Heterologous prime boost COVID 19 vaccination

open access: yesInfectious Diseases Now, 2022
Heterologous prime boost vaccination is a primary vaccination with different vaccines, most often from different vaccine platforms. It combines the immunological properties of the different vaccines and thereby induces humoral, cellular and, in some cases, mucosal response.
O Launay
exaly   +3 more sources

Willingness of college students to receive COVID-19 heterologous vaccination in Taizhou, China

open access: yesHuman Vaccines and Immunotherapeutics, 2023
This study aimed to determine the willingness of college students to choose COVID-19 heterologous vaccination and its associated influencing factors in Taizhou, China. A population-based, self-administered online questionnaire was conducted from March 15
Xiao-Qing Lin, Yan Chen, Li Lv
exaly   +2 more sources

Heterologous ChAdOx1 nCoV-19/BNT162b2 Prime-Boost Vaccination Induces Strong Humoral Responses among Health Care Workers

open access: yesVaccines, 2021
Despite limited data on safety and immunogenicity, heterologous prime-boost vaccination is currently recommended for individuals with ChAdOx1 nCoV-19 prime immunization in certain age groups.
Louise Benning   +2 more
exaly   +3 more sources

Heterologous vaccination with subunit protein vaccine induces a superior neutralizing capacity against BA.4/5‐included SARS‐CoV‐2 variants than homologous vaccination of mRNA vaccine

open access: yesMedComm, 2023
BA.4 and BA.5 (BA.4/5), the subvariants of Omicron, are more transmissible than BA.1 with more robust immune evasion capability because of its unique spike protein mutations.
Dandan Peng, Weiqi Hong, Minyang Fu
exaly   +2 more sources

Heterologous Prime-boost COVID-19 Vaccination

open access: yesJK Science, 2021
There is a significant recent international interest in heterologous prime-boost COVID-19 vaccination. It may prove useful in avoiding the supply shocks or shortages that might otherwise reduce the speed of vaccine roll-out in any country including ...
Vishal R. Tandon, Annil Mahajan
doaj   +1 more source

Immunogenicity and efficacy of          heterologous ChAdOx1–BNT162b2 vaccination [PDF]

open access: yesNature, 2021
Abstract Following severe adverse reactions in patients vaccinated with the AstraZeneca ChadOx1 (Chad) vaccine, European health authorities have recommended that patients under the age of 55 who received one dose of Chad vaccine receive a second dose of Pfizer BNT162b2 (BNT) vaccine as a booster.
Bruno Pozzetto   +36 more
openaire   +5 more sources

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