Results 41 to 50 of about 29,136 (254)

Durability of Heterologous and Homologous COVID-19 Vaccine Boosts

JAMA Network Open, 2022
Importance: Antibody responses elicited by current messenger RNA (mRNA) COVID-19 vaccines decline rapidly and require repeated boosting. Objective: To evaluate the immunogenicity and durability of heterologous and homologous prime-boost regimens involving the adenovirus vector vaccine Ad26.COV2.S and the mRNA vaccine BNT162b2.
Tan, C. Sabrina, Collier, Ai-ris Y., Yu, Jingyou, Liu, Jinyan, Chandrashekar, Abishek, McMahan, Katherine, Jacob-Dolan, Catherine, He, Xuan, Roy, Vicky, Hauser, Blake M., Munt, Jennifer E., Mallory, Michael L., Mattocks, Melissa, Powers, John M., Meganck, Rita M., Rowe, Marjorie, Hemond, Rachel, Bondzie, Esther A., Jaegle, Kate H., Baric, Ralph S., Schmidt, Aaron G., Alter, Galit, Le Gars, Mathieu, Sadoff, Jerald, Barouch, Dan H.   +24 more
openaire   +2 more sources

Heterologous ChAdOx1 nCoV-19 and mRNA-1273 Vaccination

New England Journal of Medicine, 2021
Heterologous Vaccination with ChAdOx1 nCoV-19 and mRNA-1273 Health care workers who had received a dose of ChAdOx1 nCoV-19 were offered a choice of receiving either ChAdOx1 nCoV-19 or mRNA-1273 9 t...
Johan Normark, Linnea Vikström, Yong-Dae Gwon, Ida-Lisa Persson, Alicia Edin, Tove Björsell, Andy Dernstedt, Wanda Christ, Staffan Tevell, Magnus Evander, Jonas Klingström, Clas Ahlm, Mattias Forsell   +12 more
openaire   +2 more sources

Exploring heterologous prime-boost vaccination approaches to enhance influenza control in pigs

Veterinary Research, 2020
Influenza A viruses evolve rapidly to escape host immunity. In swine, this viral evolution has resulted in the emergence of multiple H1 and H3 influenza A virus (IAV) lineages in the United States (US) pig populations.
Chong Li, Marie R. Culhane, Maxim Cheeran, Lucina Galina Pantoja, Micah L. Jansen, Deborah Amodie, Martha A. Mellencamp, Montserrat Torremorell   +7 more
doaj   +1 more source

Safety and immunogenicity of heterologous and homologous inactivated and adenoviral-vectored COVID-19 vaccine regimens in healthy adults: a prospective cohort study

Human Vaccines & Immunotherapeutics, 2022
In light of intermittent supply shortages of individual vaccines and evidence of rare but serious adverse events after vaccination, heterologous regimens for COVID-19 vaccines have gained significant interest. This study aims to assess the reactogenicity
Nasamon Wanlapakorn, Nungruthai Suntronwong, Harit Phowatthanasathian, Ritthideach Yorsaeng, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Chompoonut Auphimai, Donchida Srimuan, Thaksaporn Thatsanatorn, Suvichada Assawakosri, Sitthichai Kanokudom, Yong Poovorawan   +11 more
doaj   +1 more source

Heterologous vaccine immunogenicity, efficacy, and immune correlates of protection of a modified-live virus porcine reproductive and respiratory syndrome virus vaccine

Frontiers in Microbiology, 2022
Although porcine reproductive and respiratory syndrome virus (PRRSV) vaccines have been available in North America for almost 30 years, many vaccines face a significant hurdle: they must provide cross-protection against the highly diverse PRRSV strains ...
Jessica Proctor, Iman Wolf, David Brodsky, Lizette M. Cortes, Alba Frias-De-Diego, Glen W. Almond, Elisa Crisci, Tatiane Terumi Negrão Watanabe, James M. Hammer, Tobias Käser   +9 more
doaj   +1 more source

Heterologous vaccine interventions: boosting immunity against future pandemics

Molecular Medicine, 2021
While vaccines traditionally have been designed and used for protection against infection or disease caused by one specific pathogen, there are known off-target effects from vaccines that can impact infection from unrelated pathogens.
Daniela Marín-Hernández, Douglas F. Nixon, Nathaniel Hupert   +2 more
doaj   +1 more source

Homologous and Heterologous Prime-Boost Vaccination: Impact on Clinical Severity of SARS-CoV-2 Omicron Infection among Hospitalized COVID-19 Patients in Belgium

Vaccines, 2023
We investigated effectiveness of (1) mRNA booster vaccination versus primary vaccination only and (2) heterologous (viral vector–mRNA) versus homologous (mRNA–mRNA) prime-boost vaccination against severe outcomes of BA.1, BA.2, BA.4 or BA.5 Omicron ...
Marjan Meurisse, Lucy Catteau, Joris A. F. van Loenhout, Toon Braeye, Laurane De Mot, Ben Serrien, Koen Blot, Emilie Cauët, Herman Van Oyen, Lize Cuypers, Belgian Collaborative Group on COVID-19 Hospital Surveillance, COVID-19 Genomics Belgium Consortium, Annie Robert, Nina Van Goethem   +13 more
doaj   +1 more source

Heterologous Covid-19 vaccines intervention effect on reactogenicity

Journal of the Pakistan Medical Association, 2023
To determine the change in the occurrence of short-term vaccine reactions on the use of heterologous Covid-19 booster, a single centre short-term study of two months duration was conducted. It was designed as an interventional study with registered clinical trial number # SLCTR/2022/008.
Wajeha, Najeeb, Palvasha, Waheed, Rehana, Khadim   +2 more
openaire   +2 more sources

Safety of heterologous ChAdOx1-S/BNT162b2 primary schedule versus homologous BNT162b2 vaccination: Insights from an Italian post-marketing study, 2021

Human Vaccines & Immunotherapeutics, 2023
During COVID-19 vaccination campaign, possible ChAdOx1-S-associated risks of thrombosis with thrombocytopenia syndrome led to implement ChAdOx1-S/BNT162b2 heterologous vaccination, despite the limited information on its reactogenicity and safety.
Francesca Fortunato, Rosa Prato, Giuseppina Iannelli, Leonardo Ascatigno, Daniela Loconsole, Pier Luigi Lopalco, Domenico Martinelli   +6 more
doaj   +1 more source

Heterologous vaccination (ChAdOx1 and BNT162b2) induces a better immune response against the omicron variant than homologous vaccination

Journal of Infection and Public Health, 2023
Background: The ongoing COVID-19 pandemic has seen the emergence of numerous novel variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus.
Jaeeun Yoo, Younjeong Kim, Yu mi Cha, Jaewoong Lee, Yeon Jeong Jeong, Si-Hyun Kim, Lisa L. Maragakis, Seungok Lee   +7 more
doaj   +1 more source