Results 111 to 120 of about 32,734 (287)

Failure of vaccination to prevent outbreaks of foot-and-mouth disease

, 1996
Outbreaks of foot-and-mouth disease persist in dairy cattle herds in Saudi Arabia despite revaccination at intervals of 4-6 months. Vaccine trials provide data on antibody responses following vaccination.
Woolhouse, Mark E; id_orcid, Pearson, A., Kitching, R.P., Haydon, D T   +3 more
core   +1 more source

Neonatal BCG vaccination reduces interferon gamma responsiveness to heterologous pathogens in infants from a randomised controlled trial [PDF]

, 2020
Background Bacille Calmette-Guérin (BCG) vaccination has beneficial non-specific (heterologous) effects that protect against non-mycobacterial infections.
Messina, NL, Germano, S, Germano, Susan, Bonnicci, Rhiain, CAsalaz, Dan, Robins-Browne, R.M., Messina, Nicole, Bonnici, R, Casalaz, D., Donath, Susan, Gardiner, Kaya, Kollmann, T, Gardiner, K, Germano, S., Donath, S, Curtis, N, Curtis, Nigel, Flanagan, KL, Freyne, B, Bonnici, R., Kollmann, T., Kollmann, Toby, Netea, Mihai, Flanagan, K.L., Robins-Browne, Roy, Gardiner, K., Netea, M.G., Freyne, Bridget, Donath, S., Netea, MG, Casalaz, D, Robins-Browne, RM, Freyne, B., Curtis, N., Flanagan, Katherine, Messina, N.L.   +35 more
core   +1 more source

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang, Ping‐Hsun Wu, Li‐Yun Chang, Yu‐Ying Huang, Teng‐Hui Huang, Su‐Chu Lee, Yi‐wen Chiu, Shang‐Jyh Hwang, Tsun‐Yung Kuo, Mei‐Chuan Kuo   +9 more
wiley   +1 more source

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle

, 2006
Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle herds. In addition to increasing economic losses, the rise in bovine tuberculosis poses a human health risk. There is an
C. J. Howard, Howard, C J, Hope, J C; id_orcid, P. Sopp, J. C. Hope, Sopp, P   +5 more
core   +1 more source

Heterologous COVID-19 Vaccination and Booster with mRNA Vaccine Provide Enhanced Immune Response in Patients with Cirrhosis: A Prospective Observational Study

, 2023
This study aimed to evaluate the antibody and cellular responses to different coronavirus 2019 (COVID-19) vaccination regimens in patients with cirrhosis and to assess the antibody response after a vaccine booster.
Apichat Kaewdech, Ratchanon Sophonmanee, Naichaya Chamroonkul, Nawamin Pinpathomrat, Purilap Seepathomnarong, Bunya Seeyankem, Teerha Piratvisuth, Jomkwan Ongarj, Pimsiri Sripongpun   +8 more
core   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Heterologous prime-boost vaccination protects against EBV antigen–expressing lymphomas [PDF]

, 2019
The Epstein-Barr virus (EBV) is one of the predominant tumor viruses in humans, but so far no therapeutic or prophylactic vaccination against this transforming pathogen is available.
Taylor, Graham S, Rühl, J, Taylor, Graham S., Engelmann, C, Citterio, C, Leung, Carol S, Taylor, Graham, Khanna, R, Dzionek, A, Rühl, Julia, Dzionek, Andrzej, Wilson, Joanna B, Engelmann, Christine, Leung, Carol, Leung, Carol S., Münz, C, Dreyer, J, Wilson, Joanna B., Dreyer, Johannes, Leung, C, Khanna, Rajiv, Haigh, Tracey, Citterio, Carmen, Wilson, J, Haigh, T, Taylor, GS, Wilson, JB, Munz, Christian   +27 more
core   +1 more source

Table_1_BNT162b2 COVID-19 vaccination in children alters cytokine responses to heterologous pathogens and Toll-like receptor agonists.docx

, 2023
BackgroundVaccines can have beneficial off-target (heterologous) effects that alter immune responses to, and protect against, unrelated infections. The heterologous effects of COVID-19 vaccines have not been investigated in children.AimTo investigate ...
Nicole L. Messina (10518191), Sonja Elia (16880196), David Burgner, Christine Axelrad, Kirsten P. Perrett, Thanh D. Dang (9413306), Andrés Noé, Susie Germano, Sonja Elia, Thanh D. Dang, Nigel Curtis, Christine Axelrad (13663399), Emma Burrell (16880193), Susie Germano (466440), David Burgner (268086), Nigel Curtis (150095), Emma Burrell, Nicole L. Messina, Andrés Noé (3620534), Kirsten P. Perrett (4874821)   +19 more
core   +1 more source

Analysis of glutamine synthetase target‐site mutations and their role in endowing glufosinate‐ammonium resistance

Pest Management Science, EarlyView.
GS2.2 G255D mutation conferred enzyme‐level glufosinate insensitivity but no whole‐plant resistance, showing trade‐offs between catalytic function and herbicide binding and providing a baseline for future studies on target‐site glufosinate resistance.
Aimone Porri, Susee Sudhakar, Matheus M Noguera, Michael Betz, Jens Lerchl, Franck E Dayan, Ingo Meiners, Tino Caldarelli, Jason Norsworthy   +8 more
wiley   +1 more source

Genetic Tools in the Nakaseomyces clade for Evolutionary Comparisons of Signal Transduction Pathways

Yeast, EarlyView.
ABSTRACT The genus Nakaseomyces provides four species that are closely related but have different characteristics. For example, N. glabratus (formerly known as Candida glabrata) is a common human pathogen, whereas N. bracarensis and N. nivariensis have been isolated in clinical settings but are not common human pathogens. N.
Maria Abraham, Christine L. Iosue, Dennis D. Wykoff   +2 more
wiley   +1 more source