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Humoral and cytokine responses to a heterologous goatpox vaccine in Mithun (<i>Bos frontalis</i>): a longitudinal field study. [PDF]
Reddy GBM +13 more
europepmc +1 more source
Cross-Protection in PRRSV: Mechanisms, Limitations, and Implications for Vaccine Design. [PDF]
Raev SA +5 more
europepmc +1 more source
Trained immunity: consequences for the heterologous effects of BCG vaccination
A growing body of evidence from epidemiologic and immunologic studies have shown that in addition to target disease-specific effects, vaccines have heterologous effects towards unrelated pathogens. Like some other vaccines, bacille Calmette-Guerin (BCG) has shown in observational studies and randomized clinical trials to increase survival beyond the ...
Kleinnijenhuis, J. +2 more
openaire +4 more sources
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Vaccine, 2016
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi +8 more
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The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi +8 more
openaire +3 more sources
Cowpea mosaic virus as a vaccine carrier of heterologous antigens
Molecular Biotechnology, 2001The plant virus, cowpea mosaic virus (CPMV), has been developed as an expression and presentation system to display antigenic epitopes derived from a number of vaccine targets including infectious disease agents and tumors. These chimeric virus particles (CVPs) could represent a cost-effective and safe alternative to live replicating virus and ...
F R, Brennan, T D, Jones, W D, Hamilton
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Heterologous protection elicited by a live, attenuated, Leptospira vaccine
Veterinary Microbiology, 2018A previously-described live, attenuated vaccine (M1352, serovar Manilae, serogroup Pyrogenes) was tested in the hamster model of infection for cross-protective immunity. The vaccine elicited strong, significant cross-protection against lethal infection by strains representing four serologically distinct leptospiral serovars (Grippotyphosa, Australis ...
Gerald L. Murray +4 more
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Bulletin of Experimental Biology and Medicine, 2022
We studied the biochemical parameters of the blood of cattle after immunization against lumpy skin disease with a vaccine made from an attenuated heterologous goat pox virus (strain G20-LKV). Blood samples were obtained from animals on days 7, 14, and 21 after vaccination. The vaccine did not affect biochemical parameters of the blood.
Ye A, Bulatov +7 more
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We studied the biochemical parameters of the blood of cattle after immunization against lumpy skin disease with a vaccine made from an attenuated heterologous goat pox virus (strain G20-LKV). Blood samples were obtained from animals on days 7, 14, and 21 after vaccination. The vaccine did not affect biochemical parameters of the blood.
Ye A, Bulatov +7 more
openaire +2 more sources
A prime–boost vaccination of mice with heterologous H5N1 strains
Vaccine, 2009We evaluated the priming effect of an H5N1 pandemic vaccine in a mouse model to investigate strategies for influenza pandemic vaccination. For priming, an alum-adjuvanted inactivated whole H5N1 vaccine (NIBRG-14, clade 1) was used. As booster vaccines, several formulations of Indo05/05/2005(H5N1)PR8-IBCDC-RG2 vaccines (clades 2-1)were evaluated ...
Daisuke, Ikeno +7 more
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Heterologe Vaccination gegen Superinfekte mit Tuberkelbakterien
1961Fur Schutzimpfungen gegen bakterielle Infektionen werden homologe Vaccinen verwendet; dementsprechend gegen den tuberkulosen Infekt solche aus schwach virulenten Tuberkelbakterien. Der Vaccination mit heterologen (nicht-mycobakteriellen) Vaccinen hat man nur geringes Interesse geschenkt. Das ist berechtigt und verstandlich, soweit es sich um die Praxis
Enno Freerksen +2 more
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Heterologous Prime-Boost Vaccination in Tumor Immunotherapy
2004Most of the vaccine strategies under development use multiple immunizations with the same agent such as a viral vector encoding a tumor antigen. More recently, the concept of heterologous prime-boost immunization has been tested in animal models. This strategy involves the sequential administration of different delivery vectors encoding the same ...
Michael J. Palmowski, Caroline Smith
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