Results 241 to 250 of about 32,734 (287)

Adaptive Laboratory Evolution Unlocks Membrane Permeability as a Key Limitation in Long‐Chain Alcohol Metabolism by Pseudomonas putida KT2440

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
Pseudomonas putida KT2440 grows on polyethylene‐derived long‐chain alcohols (C16OH, C20OH) as sole carbon sources. Adaptive laboratory evolution rapidly increases growth, converging on envelope‐associated mutations. Expressing the outer‐membrane transporter AlkL recapitulates much of the evolved phenotype, identifying substrate access and membrane ...
Raul Mireles, Lianet Noda‐García
wiley   +1 more source

Engineering Pseudomonas protegens as a Targeted Antifungal‐Effector Delivery Chassis via Heterologous Type III Secretion System Reconstitution

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
A heterologous T3SS turns Pseudomonas protegens Pf‐5 into a programmable molecular syringe that delivers Bg9562 into Fusarium hyphae, suppresses fungal pathogens, enhances rhizosphere colonization and protects tomato plants from wilt. This modular platform offers a transferable strategy for next‐generation fungal biocontrol.
Yuyuan Peng   +15 more
wiley   +1 more source

Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults—A Pilot Study

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Can we boost vaccine responses in older adults? In a double‐blind, randomised, placebo‐controlled pilot study (n = 40, > 65 years), spermidine supplementation (6 mg/day, 13 weeks) was safe and significantly improved immune responses following a 3rd SARS‐CoV‐2 vaccine dose.
Ghada Alsaleh   +25 more
wiley   +1 more source

T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett   +2 more
wiley   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner   +6 more
wiley   +1 more source

A vaccination programme combining a live attenuated Salmonella Typhimurium and an autogenous inactivated Salmonella Enteritidis vaccine confers protection and reduces ovarian colonisation with the Salmonella Enteritidis isolate 7A, PT12

open access: yesAustralian Veterinary Journal, Volume 104, Issue 6, Page 395-403, June 2026.
Salmonella enterica serovar Enteritidis (SE) can colonise chicken ovaries and contaminate eggs, posing a global risk of human gastroenteritis, often linked to raw or undercooked eggs. Control options for SE outbreaks in Australia are limited; autogenous SE vaccines are commonly used, while live attenuated Salmonella Typhimurium (ST) vaccines are ...
JA Quinteros   +7 more
wiley   +1 more source

Infectious hematopoietic necrosis virus (IHNV) in fish and its consequences for fish farming: A comprehensive review

open access: yesJournal of the World Aquaculture Society, Volume 57, Issue 3, June 2026.
Abstract Viral diseases are a major concern in finfish aquaculture, leading to severe health problems. Infectious hematopoietic necrosis (IHN) is a highly transmissible systemic viral disease that primarily affects salmonids, causing significant mortality and economic losses to the salmonid farming industry.
Zahra Tulaby Dezfuly   +9 more
wiley   +1 more source

Comprehensive and Comparative Transcriptional Profiling of the Cell Wall Stress Response in Bacillus subtilis

open access: yesMolecular Microbiology, Volume 125, Issue 6, Page 506-545, June 2026.
Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang   +12 more
wiley   +1 more source

Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y‐Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon

open access: yesMolecular Plant Pathology, Volume 27, Issue 6, June 2026.
A synonymous mutation at P1 K178 attenuates PVY virulence and abolishes tobacco vein necrosis. This attenuated vector serves as a high‐efficiency plant bioreactor for the production and purification of recombinant human interferons. ABSTRACT Plant virus‐based vectors are gaining significant attention as bioreactors for recombinant protein production ...
De‐Guo Liu   +11 more
wiley   +1 more source

Rooting Conifer Genetic Research: An Accessible and Efficient Transformation System

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 4027-4040, June 2026.
ABSTRACT Conifers serve as the cornerstone of global forest ecosystems, yet their genetic transformation faces notorious challenges. To overcome the intrinsic resistance of conifer adventitious roots to Agrobacterium/Rhizobium‐mediated transformation, we systematically and iteratively engineered the binary vector by introducing chimeric Ri plasmid ...
Jing‐Jing Li   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy