Results 221 to 230 of about 29,136 (254)

Safety and immunogenicity of heterologous ChAdOx1-nCoV19 and BNT162b2 vaccination: A meta-analysis of the heterologous COVID-19 vaccination outcomes

open access: yesVaccine, 2023
Here, we systematically assessed the safety and immunogenicity of the heterologous ChAd/BNT vaccination regimens.We evaluated the immunogenicity by the geometric mean titers ratio (GMTR) of the neutralizing antibody and anti-spike IgG. The safety of heterologous ChAd/BNT vaccination was evaluated using the pooled risk ratios (RRs) calculated by the ...
Hu, Yuxuan   +9 more
exaly   +3 more sources

Heterologous vaccine effects

Vaccine, 2016
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi   +8 more
openaire   +3 more sources

Cowpea mosaic virus as a vaccine carrier of heterologous antigens

Molecular Biotechnology, 2001
The plant virus, cowpea mosaic virus (CPMV), has been developed as an expression and presentation system to display antigenic epitopes derived from a number of vaccine targets including infectious disease agents and tumors. These chimeric virus particles (CVPs) could represent a cost-effective and safe alternative to live replicating virus and ...
F R, Brennan, T D, Jones, W D, Hamilton
openaire   +2 more sources

Heterologous protection elicited by a live, attenuated, Leptospira vaccine

Veterinary Microbiology, 2018
A previously-described live, attenuated vaccine (M1352, serovar Manilae, serogroup Pyrogenes) was tested in the hamster model of infection for cross-protective immunity. The vaccine elicited strong, significant cross-protection against lethal infection by strains representing four serologically distinct leptospiral serovars (Grippotyphosa, Australis ...
Gerald L. Murray   +4 more
openaire   +2 more sources

Trained immunity: consequences for the heterologous effects of BCG vaccination

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2015
A growing body of evidence from epidemiologic and immunologic studies have shown that in addition to target disease-specific effects, vaccines have heterologous effects towards unrelated pathogens. Like some other vaccines, bacille Calmette-Guerin (BCG) has shown in observational studies and randomized clinical trials to increase survival beyond the ...
Kleinnijenhuis, J.   +2 more
openaire   +3 more sources

A prime–boost vaccination of mice with heterologous H5N1 strains

Vaccine, 2009
We evaluated the priming effect of an H5N1 pandemic vaccine in a mouse model to investigate strategies for influenza pandemic vaccination. For priming, an alum-adjuvanted inactivated whole H5N1 vaccine (NIBRG-14, clade 1) was used. As booster vaccines, several formulations of Indo05/05/2005(H5N1)PR8-IBCDC-RG2 vaccines (clades 2-1)were evaluated ...
Daisuke, Ikeno   +7 more
openaire   +2 more sources

Heterologe Vaccination gegen Superinfekte mit Tuberkelbakterien

1961
Fur Schutzimpfungen gegen bakterielle Infektionen werden homologe Vaccinen verwendet; dementsprechend gegen den tuberkulosen Infekt solche aus schwach virulenten Tuberkelbakterien. Der Vaccination mit heterologen (nicht-mycobakteriellen) Vaccinen hat man nur geringes Interesse geschenkt. Das ist berechtigt und verstandlich, soweit es sich um die Praxis
Enno Freerksen   +2 more
openaire   +1 more source

Heterologous Prime-Boost Vaccination in Tumor Immunotherapy

2004
Most of the vaccine strategies under development use multiple immunizations with the same agent such as a viral vector encoding a tumor antigen. More recently, the concept of heterologous prime-boost immunization has been tested in animal models. This strategy involves the sequential administration of different delivery vectors encoding the same ...
Michael J. Palmowski, Caroline Smith
openaire   +1 more source

To mix or not to mix? A rapid systematic review of heterologous prime–boost covid-19 vaccination

Expert Review of Vaccines, 2021
Daniel Tsung-Ning Huang   +2 more
exaly  

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