Results 201 to 210 of about 29,136 (254)
Heterologous Vaccination and Checkpoint Blockade Synergize To Induce Antileukemia Immunity. [PDF]
Manlove LS +6 more
europepmc +1 more source
GC B Cells, Tfh Cells, and Influenza bnAbs: Insights for Improving Universal Vaccine Design
ABSTRACT Antibodies are crucial for providing protection against influenza virus infection; however, protective humoral immunity is limited by antigenic drift and shift. Hence, the discovery of broadly neutralizing antibodies (bnAbs) targeting conserved epitopes on hemagglutinin protein evokes the hope of developing a universal influenza vaccine ...
Takeshi Inoue +2 more
wiley +1 more source
ABSTRACT Background ABO blood group has been associated with SARS‐CoV‐2 susceptibility. Little data exist regarding the impact of ABO and Rhesus (Rh[D]) type on breakthrough infections and antibody responses following SARS‐CoV‐2 booster vaccination. Methods This multicenter, population‐based cohort study includes individuals ≥ 18 years who received a ...
Daniela Sieghart +35 more
wiley +1 more source
Orchid genome evolution and trait innovation
Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng +8 more
wiley +1 more source
Bacterial pathogens colonise woody hosts by integrating metabolic adaptation, effector‐mediated immune suppression, cell wall remodelling and EPS‐ and toxin‐supported persistence. ABSTRACT Bacterial pathogens of woody plants represent a pervasive yet underexplored threat to global agriculture and forestry, causing devastating diseases in fruit trees ...
Antonio Arroyo‐Mateo +3 more
wiley +1 more source
Fusarium graminearum can cleave tryptamine‐derived hydroxycinnamic acid amides and convert the released tryptamine into auxin, suppressing plant defence responses; aoxΔ7—septuple knockout of copper amine oxidases blocks auxin formation. ABSTRACT The important cereal pathogen Fusarium graminearum is not only able to produce trichothecene toxins, like ...
Thomas Svoboda +12 more
wiley +1 more source
A newly identified virulence family from Pectobacterium parvum that binds plant defensive compounds (e.g., solanidine) with high affinity enhances bacterial tolerance and is required for full virulence. This trade‐off between defence and growth reveals a key host‐adaptation strategy.
Jinhui Wang +5 more
wiley +1 more source
ABSTRACT Anthracnose caused by Colletotrichum gloeosporioides is a major threat to tea cultivation; however, the molecular mechanism underlying different resistance among tea cultivars remains unclear. We identified distinct expression patterns of CsMYB82 between anthracnose‐resistant and susceptible varieties after infection with anthracnose from ...
Rui Han +14 more
wiley +1 more source
ABSTRACT Biotic stresses, particularly Verticillium wilt (VW), lead to a global decline in cotton yields. Here, we demonstrate that ectopic expression of ScALDH21, a gene from the desiccation‐tolerant moss Syntrichia caninervis Mitt. and absent in angiosperms, enhances cotton's resistance to VW.
Honglan Yang +13 more
wiley +1 more source
ABSTRACT Plant viruses are recognized as rapid and effective vectors to deliver CRISPR‐Cas reaction components into plants, a strategy termed virus‐induced gene editing (VIGE). However, VIGE is limited by the host range of the viral vectors. Development of new viral vectors to target a broad range of plant species will potentially enable the delivery ...
Fernando Merwaiss +3 more
wiley +1 more source

