Results 181 to 190 of about 29,136 (254)

SARS‐CoV‐2 Neutralization Breadth Is Shaped by Variant Exposure and Immune History

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Despite widespread COVID‐19 vaccination, emerging SARS‐CoV‐2 variants continue to evade neutralizing responses. To determine how exposure history influences neutralizing breadth against SARS‐CoV‐2, plasma collected from 46 participants in the Clinical, Virological and Immunological COVID‐19 study cohort (CVIC) was analyzed.
Greta Vizgirda, Alexander P. Underwood, Ulrik Fahnøe, Christina Sølund, Signe Lysemose Villadsen, Andrea Galli, Nina Weis, Jens Bukh   +7 more
wiley   +1 more source

Antibody Responses in Pediatric Dengue Indicate Emergence and Co‐Circulation of DENV‐3 Genotypes I and III in Myanmar and Orthoflavivirus Cross‐Reactivity

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Dengue virus (DENV) remains a major public health concern in Southeast Asia, disproportionately affecting children. In Myanmar, DENV‐3 Genotype III predominated before 2017, with Genotype I emerging thereafter. To assess the impact of this emergence on antibody responses, we analyzed paired acute and convalescent serum samples from 38 ...
Jean Claude Balingit, Khine Mya Nwe, Htin Lin, Wah Wah Aung, Ryosuke Suzuki, Yuki Takamatsu, Takeshi Urano, Aye Aye Khin, Kyaw Zin Thant, Hlaing Myat Thu, Mya Myat Ngwe Tun, Kouichi Morita   +11 more
wiley   +1 more source

Comparative effectiveness and safety of homologous two-dose ChAdOx1 versus heterologous vaccination with ChAdOx1 and BNT162b2: a cohort analysis

, 2021
Prieto-Alhambra D, Hermosilla E, Coma E, Xie J, Feng S, Cabezas C, Méndez-Boo L, Fina F, Ballo E, Martínez M, Medina-Peralta M, Argimon JM.   +11 more
europepmc   +1 more source

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang, Ping‐Hsun Wu, Li‐Yun Chang, Yu‐Ying Huang, Teng‐Hui Huang, Su‐Chu Lee, Yi‐wen Chiu, Shang‐Jyh Hwang, Tsun‐Yung Kuo, Mei‐Chuan Kuo   +9 more
wiley   +1 more source

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source

Experimental, Genomic, and Structural Evidence Supporting Putative PET‐Hydrolases in Thermophilic Bacteria Isolated From Hot Springs in Cajamarca, Peru

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Integrated microbiological, genomic, and structural analyses of bacteria isolated from a Peruvian geothermal system reveal enzymatic potential for the transformation of polyesters such as PET. This study links experimental evidence with genomic determinants and in silico analyses that support the thermophilic bacteria biodegradation capacity.
Marco A. Rivera‐Jacinto, Claudia Rodríguez‐Ulloa, Sara R. Briones‐Ramírez, Betsy Quispe‐Cruz, Sandra Carrasco‐Tarrillo, Diego A. Leonardo, Juan P. Cardenas   +6 more
wiley   +1 more source

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

MedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang, Ying Liu, Yilin Hou, Hongxia Niu   +3 more
wiley   +1 more source

Deciphering the Function and Structure of PA1216 as an S‐Adenosyl‐l‐Methionine Binding Protein Using Differential Scanning Fluorimetry and Circular Dichroism

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Microbes produce bioactive secondary metabolites as toxins, pigments, or virulence factors. These specialized compounds are produced by nonribosomal peptide synthetases (NRPS), polyketide synthases (PKS), or hybrid NRPS/PKS pathways. The genes encoding NRPS and PKS reside in biosynthetic gene clusters (BGCs), some of which have no identified ...
Amaan M. Fruitwala, Jade X. Tiszler, Daniel Watson, Mansi Sinha, Tony D. Davis   +4 more
wiley   +1 more source

Analysis of glutamine synthetase target‐site mutations and their role in endowing glufosinate‐ammonium resistance

Pest Management Science, Volume 82, Issue 8, Page 7633-7644, August 2026.
GS2.2 G255D mutation conferred enzyme‐level glufosinate insensitivity but no whole‐plant resistance, showing trade‐offs between catalytic function and herbicide binding and providing a baseline for future studies on target‐site glufosinate resistance.
Aimone Porri, Susee Sudhakar, Matheus M Noguera, Michael Betz, Jens Lerchl, Franck E Dayan, Ingo Meiners, Tino Caldarelli, Jason Norsworthy   +8 more
wiley   +1 more source

Pathogenic characteristics of a QX-like infectious bronchitis virus strain SD in chickens exposed at different ages and protective efficacy of combining live homologous and heterologous vaccination. [PDF]

Vet Res, 2020
Shao L, Zhao J, Li L, Huang X, Yang H, Cheng J, Liu C, Zhang G.   +7 more
europepmc   +1 more source