Results 191 to 200 of about 29,136 (254)
Engineered Bacterial Membranes as Next‐Generation Platforms for Cancer Immunotherapy
Small Science, Volume 6, Issue 8, August 2026.Engineered bacterial membrane platforms, including outer membrane vesicles, bacterial ghosts, genetically engineered membranes, and hybrid bacterial–tumor membranes, integrate tumor antigen presentation with intrinsic immune stimulation. These platforms promote dendritic‐cell activation, T‐cell priming, pyroptosis, and synergistic responses with ...
Hafiza Aasia Malik +4 more
wiley +1 more source
Environmental Microbiology, Volume 28, Issue 8, August 2026.Anaerobic biodegradation of benzene by sulphate‐reducing strain BzS1 was studied by combining genomics, differential proteomics and targeted metabolite analyses. Strain BzS1 has an exceptionally streamlined metabolism. A highly abundant heterotrimeric flavoprotein may add benzene to either enolpyruvate or glutaconyl‐CoA followed by channelling into the
Florin Musat +11 more
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 8, August 2026.TolC is identified as an essential component of the mixed‐linkage β‐glucan (MLG) biosynthetic machinery in Sinorhizobium meliloti, likely enabling polymer export. Co‐expression of tolC, bgsBA, and pleD* significantly enhances MLG production and enables its synthesis in non‐native bacterial hosts.
L. Ruiz‐Sáez +6 more
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 8, August 2026.NGPV VP2 is expressed made DEV as vector and experessed NGPV VP2 could form virus‐like particles. rNGPV VP2‐Cre could facilitate clearance of NGPV and provided strong protection against highly virulent DEV. ABSTRACT Since 2015, duck‐origin novel goose parvovirus (NGPV) has caused severe economic losses to the Chinese duck industry, with no licensed ...
Liu Chen +11 more
wiley +1 more source
Acta Physiologica, Volume 242, Issue 8, August 2026.ABSTRACT Aim Kidney excretion of phosphate is the gatekeeper of systemic phosphate homeostasis as evident from inborn and acquired diseases. Renal phosphate transporters are a promising target for phosphate‐lowering drugs, but molecular details of human kidney phosphate handling are largely unknown.
Ashley L. Fernandes +10 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 15, Page 4344-4363, August 2026.Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh +19 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 8, August 2026.Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
The FEBS Journal, Volume 293, Issue 16, Page 4841-4859, August 2026.Pyridoxal 5'‐phosphate (PLP), the coenzyme form of vitamin B6, is essential for amino acid metabolism. In mammals, PLP homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and ...
Nayu Kito +8 more
wiley +1 more source
The Role of CD4 T Cell Repertoire and Immune Memory Mechanisms in Vaccination and Infection Immunity
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT CD4+ T cells orchestrate adaptive immunity against respiratory viruses through functionally distinct subsets, yet the qualitative differences between vaccine‐ and infection‐induced responses remain incompletely understood. This review summarizes current evidence on how CD4+ T cell subsets shape the magnitude, breadth, and durability of ...
Masato Kubo
wiley +1 more source