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Heteroresistance to carbapenems in Acinetobacter baumannii [4]
Pournaras, S. +4 more
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Mycoses, 2017
SummaryThe concept of heteroresistance refers to the heterogeneous susceptibility to an antimicrobial drug in a microorganism population, meaning that some clones may be resistant and others are susceptible. This phenomenon has been widely studied in bacteria, but little attention has been given to its expression in fungi.
Gabriella F. Ferreira, Daniel A. Santos
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SummaryThe concept of heteroresistance refers to the heterogeneous susceptibility to an antimicrobial drug in a microorganism population, meaning that some clones may be resistant and others are susceptible. This phenomenon has been widely studied in bacteria, but little attention has been given to its expression in fungi.
Gabriella F. Ferreira, Daniel A. Santos
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Heteroresistance to cefepime in Pseudomonas aeruginosa bacteraemia
International Journal of Antimicrobial Agents, 2020Heteroresistance to antibiotic agents can lead to diagnostic and therapeutic failures; however, to date, cefepime heteroresistance (FEP-HR) in Pseudomonas aeruginosa (P. aeruginosa) bacteraemia has not been characterised. The primary goal of this study was to investigate the molecular epidemiology, mechanisms and risk factors for cefepime ...
Xiaojiong Jia +6 more
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Mechanisms and clinical relevance of bacterial heteroresistance
Nature Reviews Microbiology, 2019Antibiotic heteroresistance is a phenotype in which a bacterial isolate contains subpopulations of cells that show a substantial reduction in antibiotic susceptibility compared with the main population. Recent work indicates that heteroresistance is very common for several different bacterial species and antibiotic classes.
Dan I. Andersson +2 more
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Intrinsic clarithromycin heteroresistance in Mycobacterium avium
Journal of Infection and ChemotherapyMycobacterium avium is associated with pulmonary disease in otherwise healthy adults. Several clarithromycin-refractory cases have been reported, including some cases caused by clarithromycin-susceptible strains.To characterize the reason for the discrepancy between clinical response and antibiotic susceptibility results.We conducted population ...
Ai Ito +9 more
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Heteroresistance in Mycobacterium tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2001Drug resistance in Mycobacterium tuberculosis is often linked to specific mutations in a limited number of resistance genes. Detection of these mutations in a cultured isolate can predict the resistant phenotype. Genotypic analysis of the mycobacteria directly in a clinical specimen would result in considerable time saving for resistance prediction.To ...
H, Rinder, K T, Mieskes, T, Löscher
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