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Clinical Microbiology and Infection, 2015 Although heteroresistance is common in a wide range of microorganisms, carbapenem heteroresistance among invasive Escherichia coli infections has not been reported.
J D Sun, S F Huang, L P Zhang
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Proceedings of the National Academy of Sciences of the United States of AmericaAntibiotics are considered one of the most important contributions to clinical medicine in the last century. Due to the use and overuse of these drugs, there have been increasing frequencies of infections with resistant pathogens. One form of resistance,
Bruce R Levin +2 more
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Emergence of Heteroresistance Mycobacterium Tuberculosis in Saudi Arabia
Infectious Disorders - Drug Targets, 2020Purpose:Heteroresistant Mycobacterium tuberculosis (MTB) is defined as a group of drug-susceptible and resistant bacteria in a single clinical specimen from tuberculosis (TB) patients. Heteroresistance of MTB is considered a preliminary stage to full resistance.
Eltayib H Ahmed, Abakur +4 more
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Heteroresistance in Mycobacterium tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2001Drug resistance in Mycobacterium tuberculosis is often linked to specific mutations in a limited number of resistance genes. Detection of these mutations in a cultured isolate can predict the resistant phenotype. Genotypic analysis of the mycobacteria directly in a clinical specimen would result in considerable time saving for resistance prediction.To ...
H, Rinder, K T, Mieskes, T, Löscher
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Intrinsic clarithromycin heteroresistance in Mycobacterium avium
Journal of Infection and ChemotherapyMycobacterium avium is associated with pulmonary disease in otherwise healthy adults. Several clarithromycin-refractory cases have been reported, including some cases caused by clarithromycin-susceptible strains.To characterize the reason for the discrepancy between clinical response and antibiotic susceptibility results.We conducted population ...
Ai Ito +9 more
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Outcome of Heteroresistant Staphylococcus aureus Infections in Children
Journal of Infectious Diseases, 1987Strains of Staphylococcus aureus may display heterogeneous resistance to penicillinase-resistant penicillins in vitro [1-3]. These strains contain methicillin-susceptible organisms that have the usual characteristics of nonheteroresistant S. aureus and methicillin-resistant organisms, which grow more slowly and may escape detection under ordinary ...
M W, Kline, E O, Mason, S L, Kaplan
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Heteroresistance: A Harbinger of Future Resistance
2018During infection, bacterial populations often contain subpopulations that exhibit reduced antimicrobial susceptibility. The resulting population heterogeneity is called heteroresistance. Since a heteroresistant population can evolve into a resistant one, a heteroresistant infection is a risk factor for the development of complete resistance.
Karl Drlica, Bo Shopsin, Xilin Zhao
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Lesion Heterogeneity and Long-Term Heteroresistance in Multidrug-Resistant Tuberculosis
Journal of Infectious Diseases, 2021Qingyun Liu, Qi Jiang, Mingyu Gan
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