Results 151 to 160 of about 3,479 (180)

Polymyxin heteroresistance in Klebsiella oxytoca

Ayerakwa EA, Douglas EJ, Larrouy-Maumus G, Edwards AM, Isawumi A.   +4 more
europepmc   +1 more source

Genomic insights into extrapulmonary tuberculosis reveal enrichment of lineage 2 with high drug resistance in specific clinical phenotypes

Sharma K, Bandari A, Manjunath GK, Rastogi M, Babu AS, Ponnusamy P, Vasanthaiah S, Vasudevan K, Yadav P, George J, Kumar A, Sharma J, Sharma A, Modi M, Gupta A, Singh R, Sinha SK, Dhillon MS, Sharma M, Sharma V, Nada R, Sharma N, Pandey A, Verma R.   +23 more
europepmc   +1 more source

Mechanisms and clinical relevance of bacterial heteroresistance

Nature Reviews Microbiology, 2019
Antibiotic heteroresistance is a phenotype in which a bacterial isolate contains subpopulations of cells that show a substantial reduction in antibiotic susceptibility compared with the main population. Recent work indicates that heteroresistance is very
Dan I Andersson, Karin Hjort, Hjort Karin   +2 more
exaly   +4 more sources

Antibiotic heteroresistance in ESKAPE pathogens, from bench to bedside

Clinical Microbiology and Infection, 2023
Background: Heteroresistance refers to subpopulation-mediated differential antimicrobial susceptibility within a clonal bacterial population. Usually, it designates a resistant subpopulation identified within an isolate considered susceptible by ...
Melanie Roch, Roberto Sierra, Diego O Andrey   +2 more
exaly   +2 more sources

Antibiotic Heteroresistance in Klebsiella pneumoniae

International Journal of Molecular Sciences, 2022
Klebsiella pneumoniae is one of the most common pathogens responsible for infections, including pneumonia, urinary tract infections, and bacteremias. The increasing prevalence of multidrug-resistant K. pneumoniae was recognized in 2017 by the World Health Organization as a critical public health threat.
Karolina Stojowska-Swędrzyńska, Adrianna Łupkowska, Dorota Kuczynska-Wisnik   +2 more
exaly   +2 more sources

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Heteroresistance to cefepime in Pseudomonas aeruginosa bacteraemia

International Journal of Antimicrobial Agents, 2020
Heteroresistance to antibiotic agents can lead to diagnostic and therapeutic failures; however, to date, cefepime heteroresistance (FEP-HR) in Pseudomonas aeruginosa (P. aeruginosa) bacteraemia has not been characterised. The primary goal of this study was to investigate the molecular epidemiology, mechanisms and risk factors for cefepime ...
Xiaojiong Jia, Jianchun He, Xiaolang Tian   +2 more
exaly   +3 more sources

Heteroresistance and fungi

Mycoses, 2017
SummaryThe concept of heteroresistance refers to the heterogeneous susceptibility to an antimicrobial drug in a microorganism population, meaning that some clones may be resistant and others are susceptible. This phenomenon has been widely studied in bacteria, but little attention has been given to its expression in fungi.
Gabriella Freitas Ferreira, Daniel Assis Santos   +1 more
exaly   +3 more sources