3D printing is a transformative technology in congenital heart disease [PDF]
, 2018 Survival in congenital heart disease has steadily improved since 1938, when Dr. Robert Gross successfully ligated for the first time a patent ductus arteriosus in a 7-year-old child.
Anwar +117 more
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Palliation of a Heterotaxy Single Ventricle Neonate with Pulmonary Atresia and Obstructed TAPVR
Pediatric Cardiology, 2023 Patients born with obstructed total anomalous pulmonary venous return have a high risk of morbidity and mortality in the neonatal period, which only increases when combined with single ventricle physiology and non-cardiac congenital anomalies such as ...
Justin A. Robinson +4 more
semanticscholar +1 more source
Proceedings of the 3rd BEAT-PCD Conference and 4th PCD Training School [PDF]
, 2018 Primary ciliary dyskinesia (PCD) is a chronic suppurative airways disease that is usually recessively inherited and has marked clinical phenotypic heterogeneity.
A Onoufriadis +35 more
core +5 more sources
Left-Sided Heart Defects and Laterality Disturbance in Hypoplastic Left Heart Syndrome
Journal of Cardiovascular Development and Disease, 2023 Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease characterized by hypoplasia of left-sided heart structures. The developmental basis for restriction of defects to the left side of the heart in HLHS remains unexplained.
Hisato Yagi, Cecilia W. Lo
doaj +1 more source
Novel dominant-negative FOXJ1 mutation in a family with heterotaxy plus mouse model
Translational Pediatrics, 2023 Background Primary ciliary dyskinesia (PCD) is a clinically heterogeneous group of autosomal or, less frequently, X-chromosomal recessive inheritance syndrome of motile cilia dysfunction characterized by neonatal respiratory distress, oto-sino-pulmonary ...
L. Li +9 more
semanticscholar +1 more source
Histopathological assessment of laterality defects in zebrafish development
Animal Cells and Systems, 2021 Laterality defects during embryonic development underlie the aetiology of various clinical symptoms of neuropathological and cardiovascular disorders; however, experimental approaches to understand the underlying mechanisms are limited due to the complex
Md. Ashraf Uddin Chowdhury +6 more
doaj +1 more source
Novel use of covered stents to treat profound cyanosis in a hepatic vein exclusion Fontan
Annals of Pediatric Cardiology, 2019 Fontan completion in patients with complex cardiac anatomy, and specifically heterotaxy syndrome, can present unique physiologic considerations. For example, existing venous connections may be “unmasked” after a cavopulmonary anastomosis operation.
Sarosh P Batlivala, Makram R Ebeid
doaj +1 more source
Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects. [PDF]
, 2020 Genetic variants are the primary driver of congenital heart disease (CHD) pathogenesis. However, our ability to identify causative variants is limited.
Bernstein, Daniel +25 more
core
Appropriate Route Selection for Extracardiac Total Cavopulmonary Connection in Apicocaval Juxtaposition [PDF]
, 2012 BACKGROUND:A malpositioned heart with apicocaval juxtaposition may complicate the management of patients with functional single ventricles when total cavopulmonary connection is performed.
Abe Masakazu +9 more
core +1 more source
Rare variant of heterotaxy syndrome in childhood in pulmonology clinic
Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics), 2023 Heterotaxy syndrome is a congenital malformation in which the internal organs of the chest and abdominal cavity have an abnormal location. People suffering from this syndrome have multiple complex defects in the heart, blood vessels, spleen, liver, lungs
Y. Mizernitskiy +8 more
semanticscholar +1 more source