Results 41 to 50 of about 13,149 (176)

Late-onset fibrodysplasia ossificans progressiva with atypical presentation: A case report

Case Reports in Women's Health, 2019
Fribrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by progressive heterotopic ossification of connective tissues, episodic flare-ups and bilateral deformities of the great toe (hallux valgus).
Conor M. Cunningham, J. Matthew Royeca, Samuel W. King, Hemant Pandit   +3 more
doaj   +1 more source

A new mouse model of post-traumatic joint injury allows to identify the contribution of Gli1+ mesenchymal progenitors in arthrofibrosis and acquired heterotopic endochondral ossification

Frontiers in Cell and Developmental Biology, 2022
Complex injury and open reconstructive surgeries of the knee often lead to joint dysfunction that may alter the normal biomechanics of the joint.
Jenny Magallanes, Jenny Magallanes, Nancy Q. Liu, Jiankang Zhang, Jiankang Zhang, Yuxin Ouyang, Tadiwanashe Mkaratigwa, Tadiwanashe Mkaratigwa, Fangzhou Bian, Fangzhou Bian, Ben Van Handel, Tautis Skorka, Frank A. Petrigliano, Denis Evseenko, Denis Evseenko   +14 more
doaj   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source

Higher prearthritic activity is associated with higher long‐term activity after medial unicompartmental knee arthroplasty

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate long‐term sport participation after medial unicompartmental knee arthroplasty and determine whether recalled prearthritic activity was associated with activity at final follow‐up. Methods This retrospective study included 76 knees in 70 patients evaluated at a mean follow‐up of 116.3 ± 31.9 months. The Tegner Activity Scale
Tosca Cerasoli, Beatrice Tabanelli, Daniele Scagnol, Laura Di Maio, Maria Pia Neri, Vito Gaetano Rinaldi, Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli   +7 more
wiley   +1 more source

Musculoskeletal health among adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the burden of, and investigate prognostic factors for, osteoarthritis, osteopenia and/or osteoporosis, spondylosis, and fracture, and to investigate the effectiveness of protocols for monitoring musculoskeletal disorders and interventions for managing osteoarthritis in adults with cerebral palsy (CP).
Jennifer M. Ryan, Jessica Burke, Rachel Byrne, Emily Capellari, Christina M Marciniak, Maram Sofiany, Reuel Jalal, Mark Peterson, The Adult CP Clinical Practice Guideline Working Group, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms   +11 more
wiley   +1 more source

Clinical Aspects and Current Therapeutic Approaches for FOP

Biomedicines, 2020
Fibrodysplasia ossificans progressiva (FOP) is an extremely rare heritable disorder of connective tissues characterized by progressive heterotopic ossification in various skeletal sites.
Hiroshi Kitoh
doaj   +1 more source

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

Journal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke, Huanhuan Liu, Grace Lach, Abhishek Wajpe, Darlene Berryman, John J. Kopchick, Shouan Zhu, Patrick M. O'Connor   +7 more
wiley   +1 more source

Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles

Bone Research
Brain-derived extracellular vesicles participate in interorgan communication after traumatic brain injury by transporting pathogens to initiate secondary injury. Inflammasome-related proteins encapsulated in brain-derived extracellular vesicles can cross
Weicheng Lu, Jianfei Yan, Chenyu Wang, Wenpin Qin, Xiaoxiao Han, Zixuan Qin, Yu Wei, Haoqing Xu, Jialu Gao, Changhe Gao, Tao Ye, Franklin R. Tay, Lina Niu, Kai Jiao   +13 more
doaj   +1 more source

Effect of Keeping Caspar Retractor During Prestige LP Cervical Disc Implantation on Intra‐ and Postoperative Outcomes

Orthopaedic Surgery, EarlyView.
This study evaluated the effect of retaining the Caspar retractor during Prestige LP implantation in cervical disc arthroplasty (CDA). Although the manufacturer recommends removal, removal caused vertebral instability during endplate drilling/cutting. Retaining the retractor reduced angle fluctuations, implantation time, and fluoroscopy usage, though ...
Xiaoqiang Zhao, Xiao Yang, Minghe Yao, Kangkang Huang, Tingkui Wu, Shihao Chen, Yi Deng, Hao Liu, Beiyu Wang   +8 more
wiley   +1 more source