Results 61 to 70 of about 20,290 (216)

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Late-onset fibrodysplasia ossificans progressiva with atypical presentation: A case report

Case Reports in Women's Health, 2019
Fribrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by progressive heterotopic ossification of connective tissues, episodic flare-ups and bilateral deformities of the great toe (hallux valgus).
Conor M. Cunningham, J. Matthew Royeca, Samuel W. King, Hemant Pandit   +3 more
doaj   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

Arthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Pulse low-intensity electromagnetic field as prophylaxis of heterotopic ossification in patients with traumatic spinal cord injury [PDF]

, 2009
Background/Aim. Heterotopic ossification (HO) is an important complication of head and spinal cord injuries (SCI). Pulse low-intensity electromagnetic field (PLIMF) therapy increases blood flow to an area of pain or inflammation, bringing more oxygen to ...
Brdareski Zorica, Jevtić Miodrag, Miljković Dejan, Plavšić Aleksandra, Đurović Aleksandar   +4 more
core   +1 more source

Unrestricted kinematic alignment on the sagittal plane: Posterior tibial slope and combined flexion do not have boundaries to respect in terms of short‐term clinical outcomes and safety

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Personalized alignment in total knee arthroplasty (TKA) is gaining traction as a surgical philosophy. True personalization, however, must encompass not only the coronal plane but also the sagittal and axial planes. This study evaluates influence of the Tibial Slope (PTS) and combined flexion (CF) on outcomes in TKA performed using ...
Edoardo Franceschetti, Pietro Gregori, Stefano Campi, Marco Spatuzzi, Giancarlo Giurazza, Andrea Tanzilli, Biagio Zampogna, Matteo Formica, Umile Giuseppe Longo, Rocco Papalia   +9 more
wiley   +1 more source

Patient‐specific psychological characteristics and personality structure affect functional outcomes after surgical stabilization of acute and chronic acromioclavicular joint injuries

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of the study was to evaluate the impact of psychological factors on functional outcomes of patients undergoing isolated acromioclavicular joint (ACJ) stabilization for acute and chronic ACJ injuries. Methods Patients who underwent ACJ stabilization between January 2015 and December 2021 and had a minimum follow‐up of 2 ...
Lukas Nawid Muench, Ali Can Gunenc, Marco‐Christopher Rupp, Lisa Rahn, Frank Martetschläger, Armin Runer, Lucca Lacheta, Sebastian Siebenlist, Bastian Scheiderer   +8 more
wiley   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

Early surgery in rare knee heterotopic ossification leads to successful functional outcome: a case report

Journal of Rehabilitation Medicine - Clinical Communications
Background: Heterotopic ossification is a common complication after joint replacement surgery, such as hip or knee arthroplasty. In the intensive care unit, it is most commonly associated with traumatic brain injury or spinal cord injury.
Stijn Pierreux, Samar M. Hatem, Stijn Roggeman, Marc Schiltz   +3 more
doaj   +1 more source

Clinical Aspects and Current Therapeutic Approaches for FOP

Biomedicines, 2020
Fibrodysplasia ossificans progressiva (FOP) is an extremely rare heritable disorder of connective tissues characterized by progressive heterotopic ossification in various skeletal sites.
Hiroshi Kitoh
doaj   +1 more source

Osificaciones heterotopicas, en pacientes sometidos a remplazo total de cadera primario mediante abordaje lateral indirecto modificado, en el Hospital Militar Central de Bogotá en los años 2005-2008 [PDF]

, 2013
La formación de osificaciones heterotópicas peri articulares después de una cirugía de la cadera es un fenómeno bien conocido, su incidencia varia ampliamente desde autores que reportan 6% hasta otros que llegan al 70%.
Arbeláez A., William R., Faria M, Pedro J., Suescun M., Juan P.   +2 more
core