Results 61 to 70 of about 13,149 (176)

3D printing of cell‐free implants: A promising avenue for cartilage regeneration and joint preservation

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This article explores the potential of 3D‐printed, cell‐free implants or devices for cartilage regeneration. It highlights the benefits of using biomaterial‐driven activation and modulation of ESCPs for endogenous healing of heterogeneous tissues, addressing challenges in implant design, repair mechanisms, and regulatory hurdles to create scalable ...
Liangbin Zhou, Shangsi Chen, Boguang Yang, Yiting Lei, Hegeng Li, Haoyue Luo, Xiaoshuai Wang, Qiongjiao Zeng, Jiahui Lai, Fei Jin, Rocky S. Tuan, Zhong Alan Li   +11 more
wiley   +1 more source

M1 macrophage-derived CXCL12 drives neurogenic heterotopic ossification following spinal cord injury

Neural Regeneration Research
Patients with spinal cord injury frequently develop neurogenic heterotopic ossification, whose pathogenesis remains incompletely understood. Existing research models struggle to accurately simulate the complex pathological process.
Yulei Xie, Yaomin Luo, Xin Chen, Yinxu Wang, Wei Song, Hua Ling   +5 more
doaj   +1 more source

Nrf2–Keap1 Axis Modulation by Phytofabricated Metal Oxide Nanoparticles in Mesenchymal Stem Cell Lineage Bias

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Phytofabricated metal oxide nanoparticles may activate the Nrf2–Keap1 axis through a dual‐stimulus mechanism, coupling nanoparticle‐derived ROS with phytochemical‐mediated Keap1 modification, steering mesenchymal stem cells toward osteogenic commitment — a mechanistic framework this review consolidates from current evidence.
Muhammad Irfan, Muhammad Taha, Syed Muhammad Faizan Asghar, Muhammad Raza   +3 more
wiley   +1 more source

Effectiveness of radiotherapy to prevent recurrence of heterotopic ossification in patients with spinal cord injury and traumatic head injury: A retrospective case-controlled study

Journal of Rehabilitation Medicine, 2020
Objective: To evaluate recurrence and early post-operative complications (sepsis) following surgical excision combined with radiotherapy for trouble-some hip heterotopic ossification in patients with spinal cord injury and traumatic brain injury. Design:
Thibaud Honore, Marjorie Salga, Amandine Grelier, Philippe Denormandie, Guillaume Genet, Alain Labib, Isabelle Bonan, Francois Genet   +7 more
doaj   +1 more source

MASSIVE POSTTRAUMATIC HETEROTOPIC OSSIFICATION OF KNEE JOINT (CASE REPORT)

Travmatologiâ i Ortopediâ Rossii, 2017
Heterotopic ossification is characterized by bone tissue formation in soft tissues that possess no osteogenic properties. The authors present a clinical case of a female patient with massive heterotopic ossification in anteromedial aspect of the right ...
M. S. Ryazantsev, N. Magnitskaya, A. P. Afanasyev, D. O. Ilʼin, A. N. Logvinov, A. V. Frolov, А. V. Korolev   +6 more
doaj   +1 more source

Heterotopic Ossification in Vertebral Interlaminar/Interspinous Instrumentation: Report of a Case

Case Reports in Surgery, 2012
We present here a rare case of heterotopic ossification in interspinous/interlaminar Coflex device. The classical surgical indications for these implants are degenerative canal stenosis, discogenic low back pain, disk herniations, facet syndrome, and ...
Giuseppe Maida, Eleonora Marcati, Silvio Sarubbo   +2 more
doaj   +1 more source

Use of Calcitonin in Recalcitrant Phantom Limb Pain Complicated by Heterotopic Ossification

Pain Research and Management, 2015
A common complication following amputation is phantom sensation, which may include experiencing pain in the phantom limb. This study details the management of phantom limb pain in a 72-year-old man, in whom comorbid heterotopic ossification was present ...
Ricardo Viana, Michael WC Payne
doaj   +1 more source

Arthroscopic excision of heterotopic ossification in the rectus femoris muscle causing extra-articular anterior hip impingement

SICOT-J, 2018
Subspine impingement is an extra-articular hip impingement syndrome that usually occurs when there is abnormal contact between an enlarged or malorientated anterior inferior iliac spine (AIIS) and the distal anterior femoral neck in straight flexion of ...
Nakano Naoki, Lisenda Laughter, Khanduja Vikas   +2 more
doaj   +1 more source

Heterotopic ossification following COVID-19 infections: systematic literature review of case reports and case series

BMC Musculoskeletal Disorders
Background This review aims to study the clinical characteristics, diagnostic results, treatments, and outcomes in patients with heterotopic ossification following COVID-19 infection.
Hachem Chaitani, Laurent Fabeck, Simon Koulischer   +2 more
doaj   +1 more source

Spinal hypermobility accelerates ossification in posterior longitudinal ligaments: insights from an in vivo mouse model

Frontiers in Physiology
IntroductionOssification of the posterior longitudinal ligaments (OPLL) is characterized by heterotopic ossification in the posterior longitudinal ligament of spine.
Tao Tang, Tao Tang, Zhengya Zhu, Zhengya Zhu, Zhongyuan He, Zhongyuan He, Fuan Wang, Lin Chen, Jianfeng Li, Hongkun Chen, Jiaxiang Zhou, Jianmin Wang, Shaoyu Liu, Yunfeng Yao, Xizhe Liu, Zhiyu Zhou   +15 more
doaj   +1 more source