Results 51 to 60 of about 112,457 (202)

Amino Acid Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su   +7 more
wiley   +1 more source

Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy

open access: yesDisease Models & Mechanisms, 2018
Syngeneic, immunocompetent allograft tumor models recapitulate important aspects of the tumor microenvironment and have short tumor latency with predictable growth kinetics, making them useful for trialing novel therapeutics.
Derek J. Erstad   +11 more
doaj   +1 more source

Adenocarcinoma arising from a heterotopic pancreas in the first portion of the duodenum: a case report

open access: yesSurgical Case Reports, 2020
Background Heterotopic pancreas (HP) is defined as pancreatic tissue in organs with no anatomical continuity with the orthotopic pancreas. Based on the number of cases reported in the literature between the year 2000 and 2020, HP is rarely found causing ...
Teruya Minami   +3 more
doaj   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, Volume 36, Issue 5, September 2026.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

A Tumor-Like Lesion Mimicking Mucinous (Colloid) Carcinoma in Heterotopic Pancreas of the Prepyloric Antrum: A Formidable Challenge for Frozen Examination [PDF]

open access: yes, 2010
Context Heterotopic pancreas is defined as the presence of pancreatic tissue, outside its usual location, which lacks anatomical and vascular continuity with the pancreas proper.
Atalay, Fuat   +5 more
core   +1 more source

Heterotopic Pancreatic Tissue in the Gallbladder: a Report of a Very Rare Case

open access: yes, 2021
To date, very little is known about the underlying causes and mechanisms involved in the pathogenesis of ectopic pancreas. Heterotopic pancreatic tissue is most commonly defned as pancreatic tissue located outside the pancreatic gland in the lack
C, Taffon   +15 more
core   +1 more source

Heterotopic Pancreas Masquerading as Duplication Cyst of the Stomach A Case Report

open access: yes, 1995
Heterotopic pancreas is not an uncommon finding in surgical or autopsy specimens. It may be asymptomatic or produce mechanical obstruction, surface ulceration, and other rarer complications.
Heng Tat Leong, Florence M. F. Cheung
core   +1 more source

Gastric duplication cyst causing hypergastrinemia in an infant

open access: yesJPGN Reports, Volume 7, Issue 3, Page 428-431, August 2026.
Abstract Gastric duplication cysts are rare congenital anomalies, with fewer than 10% occurring in the stomach. We report a 14‐month‐old girl presenting with failure to thrive, recurrent emesis, hematemesis, and severe duodenitis with ulceration. Laboratory evaluation revealed marked hypergastrinemia (1781 pg/mL), and initial imaging was unrevealing ...
Nathan Bryan, Ian Leibowitz
wiley   +1 more source

Jejunal atresia due to heterotopic pancreatic intussusception

open access: yesJournal of Pediatric Surgery Case Reports, 2021
Jejunal atresia is a common cause of neonatal intestinal obstruction that requires surgical correction and may be caused by intestinal volvulus, intussusception, or internal hernia. A 1-day-old female infant was referred to our hospital for evaluation of
So-Hyun Nam, Song-Hee Han
doaj   +1 more source

FGFR Inhibitor AZD4547 Disrupts Inflammatory CAF Crosstalk With Cancer Cells and Macrophages and Attenuates Metastasis in Pancreatic Cancer

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
This study demonstrates that FGFR‐targeted inhibition by AZD4547 in inflammatory cancer‐associated fibroblasts (iCAFs) intervenes into the tumor–stroma crosstalk. AZD4547 blocks IL‐1α–induced differentiation of pancreatic stellate cells into iCAFs, impairing iCAF‐driven tumor cell differentiation, migration, and M2 macrophage polarization. Consequently,
Ahmed M. R. H. Mostafa   +3 more
wiley   +1 more source

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