Results 101 to 110 of about 15,687,915 (207)

Mutations in the gene of the Gα subunit of the heterotrimeric G protein are the cause for the brachytic1 semi-dwarf phenotype in barley and applicable for practical breeding

Hereditas, 2017
Background Short-culm mutants have been widely used in breeding programs to increase lodging resistance. In barley (Hordeum vulgare L.), several hundreds of short-culm mutants have been isolated over the years.
Ilka Braumann, Christoph Dockter, Sebastian Beier, Axel Himmelbach, Finn Lok, Udda Lundqvist, Birgitte Skadhauge, Nils Stein, Shakhira Zakhrabekova, Ruonan Zhou, Mats Hansson   +10 more
doaj   +1 more source

Opioid Modulation of Major Neurotransmitter Systems: Acute, Chronic, and Withdrawal Effects

European Journal of Neuroscience, Volume 64, Issue 9, November 2026.
Opioids are widely used but also frequently misused drugs that affect multiple neurotransmitter systems, including dopaminergic, glutamatergic, GABAergic, serotonergic, and cholinergic pathways. Opioid‐induced neuroadaptations depend on the duration of drug exposure, with distinct changes also emerging following drug discontinuation.
Daniela Novakova, Eliska Pritulova, Jiri Novotny   +2 more
wiley   +1 more source

OsYchF1 suppresses OsEF1Bγ‐mediated ER detoxification to co‐involve the growth‐maintenance trade‐off in rice

The Plant Journal, Volume 128, Issue 3, November 2026.
SUMMARY Translation elongation is a fundamental biological process, yet its direct role in stress adaptation remains unclear. In this study, we uncover a novel regulatory axis in rice involving the unconventional G protein OsYchF1, which gates the detoxification activity of the elongation factor 1Bγ (OsEF1Bγ) in the endoplasmic reticulum.
Liyang Gao, Lulu Yu, Dongyu Chen, Rongfang Li, Yuhe Wang, Yunchuan Liao, Yetao Meng, Qian Li, Ying Miao, Gefei Hao, Rui Miao   +10 more
wiley   +1 more source

Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update

, 2018
Heterotrimeric G proteins are pivotal mediators of cellular signal transduction in eukaryotic cells and abnormal G-protein signaling plays an important role in numerous diseases.
Feng, Yuxi, Heijman, Jordi; id_orcid, Abu-Taha, Issam H., Christiane Vettel, Thomas Wieland, Vettel, Christiane, Dobrev, Dobromir, Wieland, Thomas, Dobromir Dobrev, Issam H Abu-Taha, Jordi Heijman, Yuxi Feng   +11 more
core   +1 more source

Heterotrimeric G proteins containing Gβ1γ2 subunits exhibit subtype-specific mobility differences in live cells.

PLoS ONE
Heterotrimeric G proteins are key signal transducers in all eukaryotic cells. Anchored to the inner leaflet of the plasma membrane, they transmit and amplify extracellular chemical and physical signals downstream of G protein-coupled receptors.
Ondřej Kuchynka, Andrei Kovalchuk, Mia Nußbaumer, Ekaterina Sviridova, Tomáš Fessl, Alexey Bondar   +5 more
doaj   +1 more source

Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis

, 2013
Heterotrimeric G proteins couple external signals to the activation of intracellular signal transduction pathways. Agonist-stimulated guanine nucleotide exchange activity of G-protein-coupled receptors results in the exchange of G-protein-bound GDP to ...
Kortholt, Arjan; id_orcid, Keizer-Gunnink, Ineke, Kataria, Rama, Jin, Tian, Kortholt, Arjan, Xu, Xuehua, Fusetti, Fabrizia, van Haastert, Peter J M, van Haastert, Peter J. M.   +8 more
core   +1 more source

Conventional and novel Gγ protein families constitute the heterotrimeric G-protein signaling network in soybean. [PDF]

, 2011
Heterotrimeric G-proteins comprised of Gα, Gβ and Gγ proteins are important signal transducers in all eukaryotes. The Gγ protein of the G-protein heterotrimer is crucial for its proper targeting at the plasma membrane and correct functioning. Gγ proteins
Sona Pandey, Oleg Todorov, Rheannon Thompson, Swarup Roy Choudhury, Naveen C Bisht   +4 more
core   +1 more source

Heterotrimeric G-protein candidates for Ge in the ACTH secretory pathway

, 1998
The mouse AtT-20/D16-16 anterior pituitary tumour cell line was used to identify candidate heterotrimeric G-proteins for G-exocytosis (G(e)) which mediates calcium ion-stimulated adrenocorticotrophin (ACTH) secretion in this cell line.
Daniel M Felstead, Guild, Simon, Rebecca Erlich, Brian W McFerran, McFerran, BW, Erlich, R, Felstead, DM, Simon B Guild   +7 more
core   +1 more source

The Role of Arabidopsis Heterotrimeric G-Protein Subunits in MLO2 Function and MAMP-Triggered Immunity

Molecular Plant-Microbe Interactions, 2013
Heterotrimeric G-proteins, composed of Gα, Gβ, and Gγ subunits, regulate many fundamental processes in plants. In animals, ligand binding to seven transmembrane (7TM) cell surface receptors designated G-protein coupled receptors (GPCR) leads to ...
Justine Lorek, Thomas Griebel, Alan M. Jones, Hannah Kuhn, Ralph Panstruga   +4 more
doaj   +1 more source

Characterization of the heterotrimeric G protein gene families in Triticum aestivum and related species. [PDF]

3 Biotech, 2022
Gawande ND, Hamiditabar Z, Brunetti SC, Gulick PJ.   +3 more
europepmc   +1 more source