Connexins and gap junctions in the inner ear--it's not just about K⁺ recycling. [PDF]
Cell Tissue Res, 2015 Normal development, function and repair of the sensory epithelia in the inner ear are all dependent on gap junctional intercellular communication.
Jagger DJ, Forge A.
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The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice. [PDF]
Hum Mol Genet, 2010 Mutations in the GJB2 and GJB6 genes, respectively, coding for connexin26 (Cx26) and connexin30 (Cx30) proteins, are the most common cause for prelingual non-syndromic deafness in humans.
Schütz M +13 more
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J Extracell VesiclesJournal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
europepmc +2 more sources
Collagens - structure, function and biosynthesis. [PDF]
, 2003 The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Aigner, T, Gelse, K, Poschl, E
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Epidermal stem cells and skin tissue engineering in hair follicle regeneration [PDF]
, 2015 The reconstitution of a fully organized and functional hair follicle from dissociated cells propagated under defined tissue culture conditions is a challenge still pending in tissue engineering.
Balaña, Maria Eugenia +2 more
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Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration [PDF]
, 2019 10.7554/eLife.42093.001Non-canonical Wnt signaling plays a central role for coordinated cell polarization and directed migration in metazoan development. While spatiotemporally restricted activation of non-canonical Wnt-signaling drives cell polarization
Heisenberg, Carl-Philipp +5 more
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Activation of the pro-resolving receptor Fpr2 attenuates inflammatory microglial activation [PDF]
, 2017 Poster number: P-T099 Theme: Neurodegenerative disorders & ageing Activation of the pro-resolving receptor Fpr2 reverses inflammatory microglial activation Authors: Edward S Wickstead - Life Science & Technology University of Westminster/Queen Mary ...
Biggs, C.S. +7 more
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How Plasma Membrane and Cytoskeletal Dynamics Influence Single-Cell Wound Healing: Mechanotransduction, Tension and Tensegrity [PDF]
, 2016 Organisms are able to recover from injuries by replacing damaged tissues, which recover by replacing damaged cells and extracellular structures. Similarly, a cell recovers from injuries by replacing damaged components of its structural integrity: its ...
Boucher, Eric +2 more
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Supramolecular assembly and mechanical properties of dermis [PDF]
, 2007 The present work is a part of a wider research project which aims at the in vitro tissues and biohybrid generation. The process of generating biological tissues requires benchmarks in order to define the optimal set of design and performance parameters ...
Ventre, Maurizio
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Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders. [PDF]
, 2022 Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide mechanical support for plasma membranes contacting/interacting with other cells and the extracellular matrix. Keratin genes comprise the largest subset of IntFil genes.
Bruford, Elspeth A +6 more
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