Results 1 to 10 of about 88,954 (294)

Physico-Chemical Changes Induced by Gamma Irradiation on Some Structural Protein Extracts

Biomolecules, 2023
In this study, the effect of gamma irradiation (10 kGy) on proteins extracted from animal hide, scales, and wool was evidenced by calorimetric (μDSC) and spectroscopic (IR, circular dichroism, and EPR) methods.
Maria Stanca, Carmen Gaidau, Traian Zaharescu, George-Alin Balan, Iulia Matei, Aurica Precupas, Anca Ruxandra Leonties, Gabriela Ionita   +7 more
doaj   +1 more source

CD44 Staining of Cancer Stem-Like Cells Is Influenced by Down-Regulation of CD44 Variant Isoforms and Up-Regulation of the Standard CD44 Isoform in the Population of Cells That Have Undergone Epithelial-to-Mesenchymal Transition [PDF]

, 2013
PMCID: PMC3577706This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Biddle, A, Fazil, B, Gammon, L, Mackenzie, IC   +3 more
core   +7 more sources

KVarPredDB: a database for predicting pathogenicity of missense sequence variants of keratin genes associated with genodermatoses

Human Genomics, 2020
Background Germline variants of ten keratin genes (K1, K2, K5, K6A, K6B, K9, K10, K14, K16, and K17) have been reported for causing different types of genodermatoses with an autosomal dominant mode of inheritance.
Yuyi Ying, Lu Lu, Santasree Banerjee, Lizhen Xu, Qiang Zhao, Hao Wu, Ruiqi Li, Xiao Xu, Hua Yu, Dante Neculai, Yongmei Xi, Fan Yang, Jiale Qin, Chen Li   +13 more
doaj   +1 more source

Longitudinal association of atopic dermatitis progression and keratin 6A

Scientific Reports, 2022
Atopic dermatitis is a common skin disease characterized by loss of skin integrity. Risk and severity have been associated with genetic variation especially with respect to the filaggrin gene, suggesting the importance of skin barrier function in atopic ...
Angela Y. Zhu, Nandita Mitra, David J. Margolis   +2 more
doaj   +1 more source

Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties. [PDF]

, 2012
A methicillin-resistant Staphylococcus aureus (MRSA) clone known as ST398 has emerged as a major cause of acute infections in individuals who have close contact with livestock.
Alikhan, Armand-Lefevre, Bens, Bhat, Bootsma, Castillo-Ramirez, Crombe, Cuny, DelVecchio, Devriese, Fan, Graveland, Hasman, Herron-Olson, Kaneko, Kapatral, Khanna, Leonard, Lowder, Lowy, McCarthy, McCarthy, Phillips, Rasigade, Rocha, Schijffelen, Stegger, Sung, Tatusov, Uhlemann, Uhlemann, van Belkum, van Cleef, van Loo, van Wamel, Viana, Voss, Walsh, Wassenberg, Witte   +39 more
core   +1 more source

Ovine keratome: identification, localisation and genomic organisation of keratin and keratin‐associated proteins [PDF]

Animal Genetics, 2018
SummaryWool is composed primarily of proteins belonging to the keratin family. These include the keratins and keratin‐associated proteins (KAPs) that are responsible for the structural and mechanical properties of wool fibre. Although all human keratin and KAP genes have been annotated, many of their ovine counterparts remain unknown and even less is ...
Z, Yu, J E, Plowman, P, Maclean, J E, Wildermoth, R, Brauning, J C, McEwan, N J, Maqbool   +6 more
openaire   +2 more sources

Tissue-Specific Transcriptomes Reveal Gene Expression Trajectories in Two Maturing Skin Epithelial Layers in Zebrafish Embryos. [PDF]

, 2019
Epithelial cells are the building blocks of many organs, including skin. The vertebrate skin initially consists of two epithelial layers, the outer periderm and inner basal cell layers, which have distinct properties, functions, and fates.
Cokus, Shawn J, De La Torre, Maricruz, Medina, Eric F, Ramirez-Gutierrez, Joselyn, Rasmussen, Jeffrey P, Sagasti, Alvaro, Wang, Fang   +6 more
core   +2 more sources

Identification of the ovine keratin-associated protein KAP1-2 gene (KRTAP1-2). [PDF]

Experimental dermatology, 2012
Keratin-associated proteins (KAPs) are a major component of wool and other keratin-containing tissues. While four KAP1-n proteins have been identified in sheep, only three genes have been described encoding KAP1-1, KAP1-3 and KAP1-4. Here, we used a sequence conserved across the known KAP1-n genes to search the inaugural Ovine Genome Sequence (v1.0 ...
Gong, H, Zhou, Huitong, Yu, Z, Dyer, J, Plowman, J, Hickford, Jonathan   +5 more
openaire   +3 more sources

Sulphur-isotope compositions of pig tissues from a controlled feeding study [PDF]

, 2017
Sulphur-isotope determinations are becoming increasingly useful for palaeodietary reconstruction, but knowledge of isotopic discrimination between diet and various tissues remains inadequate. In this study, we explore the sensitivity of δ34Stissue values
Evershed, Richard P., Lewis, Jamie, Miller, Bevis, Newton, Jason, Stewart, Alan, Tarlton, John F., Webb, Emily C.   +6 more
core   +2 more sources

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation [PDF]

, 2020
Aberrant detection of endogenous nucleic acids by the immune system can cause inflammatory disease. The scaffold function of the signaling kinase RIPK1 limits spontaneous activation of the nucleic acid sensor ZBP1.
De Munck, Jolien, de Reuver, Richard, Declercq, Wim, Devos, Michael, Dierick, Evelien, Gilbert, Barbara, Lefebvre, Sylvie, Maelfait, Jonathan, Nemegeer, Josephine, Rehwinkel, Jan, Tanghe, Giel, Vandenabeele, Peter, Verheirstraeten, Maud   +12 more
core   +2 more sources