Results 241 to 250 of about 214,100 (302)

Germline de novo mutation rate of the highly heterozygous amphioxus genome. [PDF]

Mol Biol Evol
Xue J, Tao L, Cao J, Wu L, Li G, Li C.
europepmc   +1 more source

BALANCE, HETEROZYGOSITY AND DEVELOPMENTAL STABILITY

Cold Spring Harbor Symposia on Quantitative Biology, 1955
openaire   +2 more sources

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Host immunogenetic variation and gut microbiome functionality in a wild vertebrate population. [PDF]

Microbiome
Lee CZ, Worsley SF, Davies CS, Komdeur J, Hildebrand F, Dugdale HL, Richardson DS.   +6 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Genome-wide assessment of genetic diversity and selective signatures in sunflower (Helianthus annuus L.) using a 10 K SNP array. [PDF]

Sci Rep
Darvishzadeh R, Alipour H, Türkoğlu A, Haliloğlu K, Fatanatvash S.   +4 more
europepmc   +1 more source

Genetic Diversity and Collection Structure Studies of Sesame (<i>Sesamum indicum</i> L.) Accessions Across Ethiopian Research Centers. [PDF]

Genes (Basel)
Gelashe FB, Ndeve AD, Menamo TM, Gandhi H, Chiulele RM.   +4 more
europepmc   +1 more source

Bipolar, not tetrapolar: mating system determination in Inonotus hispidus through genomic and phenotypic analysis. [PDF]

Appl Microbiol Biotechnol
Chen Y, Li S, Zhang J, Jiang Y, Zhao M, Hou Z, Huang C.   +6 more
europepmc   +1 more source

Haplotype-Resolved Genome of the Critically Endangered, Paleo-endemic Tree, Eidothea hardeniana. [PDF]

Genome Biol Evol
Soni A, Furtado A, Rossetto M, Henry RJ.
europepmc   +1 more source

Domestication drives repeated evolution of sexual-asexual life cycle trade-offs in yeast. [PDF]

Proc Natl Acad Sci U S A
Becerra-Rodríguez C, Thiele P, Brach G, Dutta A, Garin M, Tan G, Loegler V, Friedrich A, Andrews B, Boone C, Schacherer J, Hou J.   +11 more
europepmc   +1 more source